Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?

Co-occurrences of neurodegenerative diseases in normal pressure hydrocephalus (NPH) is a remarkable topic of discussion, which has been mentioned in recent studies and it was also emphasized by the International Society for Hydrocephalus and Cerebrospinal Fluid Disorder. In this report, I illustrate...

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Main Author: Halil Onder
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2020-04-01
Series:Indian Journal of Neurosurgery
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1708080
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author Halil Onder
author_facet Halil Onder
author_sort Halil Onder
collection DOAJ
description Co-occurrences of neurodegenerative diseases in normal pressure hydrocephalus (NPH) is a remarkable topic of discussion, which has been mentioned in recent studies and it was also emphasized by the International Society for Hydrocephalus and Cerebrospinal Fluid Disorder. In this report, I illustrate two remarkable cases which were initially diagnosed with idiopathic normal pressure hydrocephalus (iNPH) and ventriculoperitoneal (VP) shunt surgery was performed, which yielded significant improvement in the clinic of both patients in the short-term period. However, in the long-term follow-up, both of them deteriorated, and re-evaluation of the neurological examination and neuroimaging data yielded the full clinical picture of progressive supranuclear palsy (PSP). Via the illustration of these cases and related literature data, I rediscuss some related hypotheses about the co-occurrence of these two conditions of hydrocephalus and PSP. I also suggest some distinct discussions to be clarified in future studies.
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spelling doaj.art-19742c6de5f64560a6e933c2537f9b712022-12-21T23:15:50ZengThieme Medical Publishers, Inc.Indian Journal of Neurosurgery2277-954X2277-91672020-04-0190318819210.1055/s-0040-1708080Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?Halil Onder0Department of Neurology, Yozgat City Hospital, Yozgat, TurkeyCo-occurrences of neurodegenerative diseases in normal pressure hydrocephalus (NPH) is a remarkable topic of discussion, which has been mentioned in recent studies and it was also emphasized by the International Society for Hydrocephalus and Cerebrospinal Fluid Disorder. In this report, I illustrate two remarkable cases which were initially diagnosed with idiopathic normal pressure hydrocephalus (iNPH) and ventriculoperitoneal (VP) shunt surgery was performed, which yielded significant improvement in the clinic of both patients in the short-term period. However, in the long-term follow-up, both of them deteriorated, and re-evaluation of the neurological examination and neuroimaging data yielded the full clinical picture of progressive supranuclear palsy (PSP). Via the illustration of these cases and related literature data, I rediscuss some related hypotheses about the co-occurrence of these two conditions of hydrocephalus and PSP. I also suggest some distinct discussions to be clarified in future studies.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1708080normal pressure hydrocephalusprogressive supranuclear palsyneurodegenerative disease
spellingShingle Halil Onder
Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?
Indian Journal of Neurosurgery
normal pressure hydrocephalus
progressive supranuclear palsy
neurodegenerative disease
title Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?
title_full Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?
title_fullStr Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?
title_full_unstemmed Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?
title_short Progressive Supranuclear Palsy: A Crucial Co-occurrence in Normal Pressure Hydrocephalus or an Etiology of Hydrocephalic Presentation?
title_sort progressive supranuclear palsy a crucial co occurrence in normal pressure hydrocephalus or an etiology of hydrocephalic presentation
topic normal pressure hydrocephalus
progressive supranuclear palsy
neurodegenerative disease
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1708080
work_keys_str_mv AT halilonder progressivesupranuclearpalsyacrucialcooccurrenceinnormalpressurehydrocephalusoranetiologyofhydrocephalicpresentation