Viperin mutation is linked to immunity, immune cell dynamics, and metabolic alteration during VHSV infection in zebrafish

Viperin mutation is linked to immunity, immune cell dynamics, and metabolic alteration during VHSV infection in zebrafish

Viperin is a prominent antiviral protein found in animals. The primary function of Viperin is the production of 3’-deoxy-3’,4’-didehydro-cytidine triphosphate (ddhCTP), an inhibitory nucleotide involved in viral RNA synthesis. Studies in mammalian models have suggested that ddhCTP interferes with me...

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Bibliographic Details
Main Authors: K. A. S. N. Shanaka, Sumi Jung, K. P. Madushani, Myoung-Jin Kim, Jehee Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
VHSV
RNA virus
Viperin
zebrafish
antiviral protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1327749/full

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