Acute Pesticide Poisoning in Children: A Review of 50 Cases
Background: Pesticide poisoning is very common in Tunisia. Various factors are involved in the analysis of the clinical presentations and the severity of this condition. Major factors are the chemical nature of the pesticides and the quantity entered the body. Methods: This is a retrospective study...
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| Format: | Article |
| Language: | English |
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Arak University of Medical Sciences
2018-11-01
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| Series: | Iranian Journal of Toxicology |
| Subjects: | |
| Online Access: | http://ijt.arakmu.ac.ir/article-1-709-en.pdf |
| _version_ | 1811266927580938240 |
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| author | Fatma Khalsi* Ines Trablesi Imen Belhadj Nozha Brahmi Samia Hamouda Khedija Boussetta |
| author_facet | Fatma Khalsi* Ines Trablesi Imen Belhadj Nozha Brahmi Samia Hamouda Khedija Boussetta |
| author_sort | Fatma Khalsi* |
| collection | DOAJ |
| description | Background: Pesticide poisoning is very common in Tunisia. Various factors are involved in the analysis of the clinical presentations and the severity of this condition. Major factors are the chemical nature of the pesticides and the quantity entered the body.
Methods: This is a retrospective study, reporting the pediatric cases that presented to us with signs and symptoms of pesticide poisoning. Fifty cases pesticide poisoning were admitted to the hospital between January 2013 and October 2016.
Results: A total of 50 pediatric cases were included in this study with the mean age of 3 years and 4months. The poisoning was accidental in 49 cases and self-inflicted in one, with the mode being oral (N=45), respiratory (N=2) and cutaneous (N=3). The average duration of hospital care for these patients was 2 hours and 30 minutes (range: 30 min-24 hr). The clinical manifestations of poisoning noted were due to muscarinic and nicotinic receptors inhibition. Upon clinical examination, 29 patients had no pesticide in the gastric lavage fluid and urine and demonstrated no abnormal cholinesterase activity. The therapeutic management was mainly symptomatic with antidote medications prescribed (atropine and oxime). All patients had favorable outcomes and no death occurred.
Conclusion: This study demonstrated the frequency of pesticide poisoning in a pediatric setting and the importance of early management. Optimal therapeutic approaches were evaluated, demonstrating that prevention still remains the best solution in such cases. |
| first_indexed | 2024-04-12T20:52:07Z |
| format | Article |
| id | doaj.art-19796590a6e845eea7336b518a0df76b |
| institution | Directory Open Access Journal |
| issn | 2008-2967 2251-9459 |
| language | English |
| last_indexed | 2024-04-12T20:52:07Z |
| publishDate | 2018-11-01 |
| publisher | Arak University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Toxicology |
| spelling | doaj.art-19796590a6e845eea7336b518a0df76b2022-12-22T03:17:05ZengArak University of Medical SciencesIranian Journal of Toxicology2008-29672251-94592018-11-011262731Acute Pesticide Poisoning in Children: A Review of 50 CasesFatma Khalsi*0 Ines Trablesi1 Imen Belhadj 2Nozha Brahmi 3Samia Hamouda 4Khedija Boussetta 5Department of Pediatrics B, Faculty of Medicine, University of Tunis El Manar. Tunis, Tunisia.*Corresponding Author: E-mail: khalsif@gmail.comDepartment of Pediatrics B, Faculty of Medicine, University of Tunis El Manar. Tunis, Tunisia.Department of Pediatrics B, Faculty of Medicine, University of Tunis El Manar. Tunis, Tunisia.Professor of Toxicology, Emergency Medical Assistance Center of Tunis, Faculty of Medicine, University Tunis El Manar. Tunis, Tunisia.Department of Pediatrics B, Faculty of Medicine, University of Tunis El Manar. Tunis, Tunisia.Department of Pediatrics B, Faculty of Medicine, University of Tunis El Manar. Tunis, Tunisia.Background: Pesticide poisoning is very common in Tunisia. Various factors are involved in the analysis of the clinical presentations and the severity of this condition. Major factors are the chemical nature of the pesticides and the quantity entered the body. Methods: This is a retrospective study, reporting the pediatric cases that presented to us with signs and symptoms of pesticide poisoning. Fifty cases pesticide poisoning were admitted to the hospital between January 2013 and October 2016. Results: A total of 50 pediatric cases were included in this study with the mean age of 3 years and 4months. The poisoning was accidental in 49 cases and self-inflicted in one, with the mode being oral (N=45), respiratory (N=2) and cutaneous (N=3). The average duration of hospital care for these patients was 2 hours and 30 minutes (range: 30 min-24 hr). The clinical manifestations of poisoning noted were due to muscarinic and nicotinic receptors inhibition. Upon clinical examination, 29 patients had no pesticide in the gastric lavage fluid and urine and demonstrated no abnormal cholinesterase activity. The therapeutic management was mainly symptomatic with antidote medications prescribed (atropine and oxime). All patients had favorable outcomes and no death occurred. Conclusion: This study demonstrated the frequency of pesticide poisoning in a pediatric setting and the importance of early management. Optimal therapeutic approaches were evaluated, demonstrating that prevention still remains the best solution in such cases.http://ijt.arakmu.ac.ir/article-1-709-en.pdfAtropineOrganophosphatesOximePediatric CasesPoisoningPreventive Management |
| spellingShingle | Fatma Khalsi* Ines Trablesi Imen Belhadj Nozha Brahmi Samia Hamouda Khedija Boussetta Acute Pesticide Poisoning in Children: A Review of 50 Cases Iranian Journal of Toxicology Atropine Organophosphates Oxime Pediatric Cases Poisoning Preventive Management |
| title | Acute Pesticide Poisoning in Children: A Review of 50 Cases |
| title_full | Acute Pesticide Poisoning in Children: A Review of 50 Cases |
| title_fullStr | Acute Pesticide Poisoning in Children: A Review of 50 Cases |
| title_full_unstemmed | Acute Pesticide Poisoning in Children: A Review of 50 Cases |
| title_short | Acute Pesticide Poisoning in Children: A Review of 50 Cases |
| title_sort | acute pesticide poisoning in children a review of 50 cases |
| topic | Atropine Organophosphates Oxime Pediatric Cases Poisoning Preventive Management |
| url | http://ijt.arakmu.ac.ir/article-1-709-en.pdf |
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