Assessment of breast density in women from different regions of Brazil
In many countries, there is an interest in determining the location of the women with the highest breast density. This investigation is important for optimize screening for breast cancer for women with dense breasts as other imaging modalities since 2D mammography is not very efficient on this type...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-06-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844021013013 |
| _version_ | 1818614470404997120 |
|---|---|
| author | Camila Engler Lucas Paixão Luiza Freire de Souza Margarita Chevalier Maria do Socorro Nogueira |
| author_facet | Camila Engler Lucas Paixão Luiza Freire de Souza Margarita Chevalier Maria do Socorro Nogueira |
| author_sort | Camila Engler |
| collection | DOAJ |
| description | In many countries, there is an interest in determining the location of the women with the highest breast density. This investigation is important for optimize screening for breast cancer for women with dense breasts as other imaging modalities since 2D mammography is not very efficient on this type of breast. The objective of this study was to evaluate the variations in breast density in Brazilian women of different regions of Brazil. The mammographic images were taken from four regions of Brazil. The images, in the cranial caudal (CC) projection, were separated into intervals of compressed breast thickness (CBT) and patient age and were analysed by the software VolparaDensity, where volumetric breast density (VBD) calculations were performed. For each interval, null hypothesis tests for the mean difference between the VBD from the four regions of Brazil were performed. The paired tests indicated that there was a significant difference in the VBD of the women in the different regions of Brazil, with variations from 11.05% to 36.73%. Higher VBD was observed for women living in the Southeast region, followed by the Midwest, Northeast, and North regions. The Brazilian IBGE data show that the most urbanised region in Brazil is the Southeast, which coincides with the second highest rate of breast cancer in Brazil, according to the Brazilian National Cancer Institute (INCA). It is also known that breast cancer is strongly related to breast density; therefore, the results of this work support the data presented by federal agencies demonstrating that women living in the most urbanised region of Brazil (e.g., Southeast) present the highest breast density. |
| first_indexed | 2024-12-16T16:18:31Z |
| format | Article |
| id | doaj.art-1979b5bc0eeb41aeb6fa9a8c80f99008 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-16T16:18:31Z |
| publishDate | 2021-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-1979b5bc0eeb41aeb6fa9a8c80f990082022-12-21T22:24:59ZengElsevierHeliyon2405-84402021-06-0176e07198Assessment of breast density in women from different regions of BrazilCamila Engler0Lucas Paixão1Luiza Freire de Souza2Margarita Chevalier3Maria do Socorro Nogueira4Laboratory of Radioprotection Applied to Mammography, Nuclear Technology Development Center, Belo Horizonte, Brazil; Corresponding author.Anatomy and Imaging Department, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, BrazilLaboratory of Radioprotection Applied to Mammography, Nuclear Technology Development Center, Belo Horizonte, BrazilDepartment of Radiology, Universidad Complutense de Madrid, Madrid, SpainLaboratory of Radioprotection Applied to Mammography, Nuclear Technology Development Center, Belo Horizonte, BrazilIn many countries, there is an interest in determining the location of the women with the highest breast density. This investigation is important for optimize screening for breast cancer for women with dense breasts as other imaging modalities since 2D mammography is not very efficient on this type of breast. The objective of this study was to evaluate the variations in breast density in Brazilian women of different regions of Brazil. The mammographic images were taken from four regions of Brazil. The images, in the cranial caudal (CC) projection, were separated into intervals of compressed breast thickness (CBT) and patient age and were analysed by the software VolparaDensity, where volumetric breast density (VBD) calculations were performed. For each interval, null hypothesis tests for the mean difference between the VBD from the four regions of Brazil were performed. The paired tests indicated that there was a significant difference in the VBD of the women in the different regions of Brazil, with variations from 11.05% to 36.73%. Higher VBD was observed for women living in the Southeast region, followed by the Midwest, Northeast, and North regions. The Brazilian IBGE data show that the most urbanised region in Brazil is the Southeast, which coincides with the second highest rate of breast cancer in Brazil, according to the Brazilian National Cancer Institute (INCA). It is also known that breast cancer is strongly related to breast density; therefore, the results of this work support the data presented by federal agencies demonstrating that women living in the most urbanised region of Brazil (e.g., Southeast) present the highest breast density.http://www.sciencedirect.com/science/article/pii/S2405844021013013MammographyBreast densityBreast cancerSpecific screening |
| spellingShingle | Camila Engler Lucas Paixão Luiza Freire de Souza Margarita Chevalier Maria do Socorro Nogueira Assessment of breast density in women from different regions of Brazil Heliyon Mammography Breast density Breast cancer Specific screening |
| title | Assessment of breast density in women from different regions of Brazil |
| title_full | Assessment of breast density in women from different regions of Brazil |
| title_fullStr | Assessment of breast density in women from different regions of Brazil |
| title_full_unstemmed | Assessment of breast density in women from different regions of Brazil |
| title_short | Assessment of breast density in women from different regions of Brazil |
| title_sort | assessment of breast density in women from different regions of brazil |
| topic | Mammography Breast density Breast cancer Specific screening |
| url | http://www.sciencedirect.com/science/article/pii/S2405844021013013 |
| work_keys_str_mv | AT camilaengler assessmentofbreastdensityinwomenfromdifferentregionsofbrazil AT lucaspaixao assessmentofbreastdensityinwomenfromdifferentregionsofbrazil AT luizafreiredesouza assessmentofbreastdensityinwomenfromdifferentregionsofbrazil AT margaritachevalier assessmentofbreastdensityinwomenfromdifferentregionsofbrazil AT mariadosocorronogueira assessmentofbreastdensityinwomenfromdifferentregionsofbrazil |