Expression of p53 protein in pituitary adenomas

Expression of p53 protein in pituitary adenomas

Inactivating mutations of TP53, a tumor suppressor gene, are associated with abnormal cell proliferation. Although p53 expression is common in many human malignancies, p53 protein has seldom been evaluated in pituitary tumors. When detected, the percentage of p53-positive cells is low, and, in gener...

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Bibliographic Details
Main Authors: Oliveira M.C., Marroni C.P., Pizarro C.B., Pereira-Lima J.F., Barbosa-Coutinho L.M., Ferreira N.P.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2002-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Pituitary
Pituitary adenoma
Invasive adenoma
p53
Immunohistochemistry
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000500008

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