IHF and Fis as <i>Escherichia coli</i> Cell Cycle Regulators: Activation of the Replication Origin <i>oriC</i> and the Regulatory Cycle of the DnaA Initiator

IHF and Fis as <i>Escherichia coli</i> Cell Cycle Regulators: Activation of the Replication Origin <i>oriC</i> and the Regulatory Cycle of the DnaA Initiator

This review summarizes current knowledge about the mechanisms of timely binding and dissociation of two nucleoid proteins, IHF and Fis, which play fundamental roles in the initiation of chromosomal DNA replication in <i>Escherichia coli</i>. Replication is initiated from a unique replica...

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Bibliographic Details
Main Authors: Kazutoshi Kasho, Shogo Ozaki, Tsutomu Katayama
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
DNA replication
initiation
DnaA
<i>oriC</i>
nucleoid associated proteins
IHF
Online Access:https://www.mdpi.com/1422-0067/24/14/11572

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