Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease
Abstract To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyz...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-13404-w |
| _version_ | 1811343470538784768 |
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| author | Dmitrij Kravchenko Christopher Hart Stephan Garbe Julian A. Luetkens Alexander Isaak Narine Mesropyan Mathieu Vergnat Judith Leyens Ulrike Attenberger Daniel Kuetting |
| author_facet | Dmitrij Kravchenko Christopher Hart Stephan Garbe Julian A. Luetkens Alexander Isaak Narine Mesropyan Mathieu Vergnat Judith Leyens Ulrike Attenberger Daniel Kuetting |
| author_sort | Dmitrij Kravchenko |
| collection | DOAJ |
| description | Abstract To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyzed regarding dose length product (DLP) and effective dose (ED) after undergoing cardiothoracic CT imaging. Scan parameters were adjusted on a dual source/detector CT (DSCT) to minimize radiation dose while maintaining adequate quality. Image acquisition was performed at 70% of the R–R interval. Dose reducing measures included prospective electrocardiogram gating, utilizing slow injection velocities and foregoing bolus tracking during contrast injection. Image quality was assessed for artefacts, vessel definition, and noise on a 5-point scale (1 non-diagnostic, 5 excellent). Series were scored on a 0-to-3-point scale regarding answered clinical questions (0 non-diagnostic, 3 all clinical questions could be answered). The median DLP was 5.2 mGy*cm (IQR 3.5–7.8) leading to a median ED of 0.20 mSv (IQR 0.14–0.30). On average the acquired images scored 13.3 ± 2.1 (SD) out of a maximum 15 points with an intraclass correlation coefficient (ICC) of 0.94. All acquired series were able to fully answer all clinical questions scoring maximum points (ICC 1.0). Dual source high pitch CT protocols combined with custom contrast agent injection protocols in pediatric patients with CHD delivered sufficiently high diagnostic imaging quality combined with low submilisievert radiation doses. Prospective high pitch imaging is a reliable method for depiction of cardiac anatomy even in very young pediatric CHD patients with elevated heart rates. |
| first_indexed | 2024-04-13T19:29:43Z |
| format | Article |
| id | doaj.art-1981e4829732444785c452e17c4b7bba |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T19:29:43Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-1981e4829732444785c452e17c4b7bba2022-12-22T02:33:13ZengNature PortfolioScientific Reports2045-23222022-06-011211910.1038/s41598-022-13404-wImage quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart diseaseDmitrij Kravchenko0Christopher Hart1Stephan Garbe2Julian A. Luetkens3Alexander Isaak4Narine Mesropyan5Mathieu Vergnat6Judith Leyens7Ulrike Attenberger8Daniel Kuetting9Department of Diagnostic and Interventional Radiology, University Hospital BonnDepartment of Diagnostic and Interventional Radiology, University Hospital BonnDepartment of Diagnostic and Interventional Radiology, University Hospital BonnDepartment of Diagnostic and Interventional Radiology, University Hospital BonnDepartment of Diagnostic and Interventional Radiology, University Hospital BonnDepartment of Diagnostic and Interventional Radiology, University Hospital BonnDepartment of Pediatric Cardiothoracic Surgery, Children’s Hospital, University of BonnDepartment of Neonatology and Pediatric Intensive Care, Children’s Hospital, University of BonnDepartment of Diagnostic and Interventional Radiology, University Hospital BonnDepartment of Diagnostic and Interventional Radiology, University Hospital BonnAbstract To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyzed regarding dose length product (DLP) and effective dose (ED) after undergoing cardiothoracic CT imaging. Scan parameters were adjusted on a dual source/detector CT (DSCT) to minimize radiation dose while maintaining adequate quality. Image acquisition was performed at 70% of the R–R interval. Dose reducing measures included prospective electrocardiogram gating, utilizing slow injection velocities and foregoing bolus tracking during contrast injection. Image quality was assessed for artefacts, vessel definition, and noise on a 5-point scale (1 non-diagnostic, 5 excellent). Series were scored on a 0-to-3-point scale regarding answered clinical questions (0 non-diagnostic, 3 all clinical questions could be answered). The median DLP was 5.2 mGy*cm (IQR 3.5–7.8) leading to a median ED of 0.20 mSv (IQR 0.14–0.30). On average the acquired images scored 13.3 ± 2.1 (SD) out of a maximum 15 points with an intraclass correlation coefficient (ICC) of 0.94. All acquired series were able to fully answer all clinical questions scoring maximum points (ICC 1.0). Dual source high pitch CT protocols combined with custom contrast agent injection protocols in pediatric patients with CHD delivered sufficiently high diagnostic imaging quality combined with low submilisievert radiation doses. Prospective high pitch imaging is a reliable method for depiction of cardiac anatomy even in very young pediatric CHD patients with elevated heart rates.https://doi.org/10.1038/s41598-022-13404-w |
| spellingShingle | Dmitrij Kravchenko Christopher Hart Stephan Garbe Julian A. Luetkens Alexander Isaak Narine Mesropyan Mathieu Vergnat Judith Leyens Ulrike Attenberger Daniel Kuetting Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease Scientific Reports |
| title | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
| title_full | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
| title_fullStr | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
| title_full_unstemmed | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
| title_short | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
| title_sort | image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
| url | https://doi.org/10.1038/s41598-022-13404-w |
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