The double-edged sword of evolution

Two gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease.

Bibliographic Details
Main Authors: Etty Kruzel-Davila, Karl Skorecki
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/29056
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author Etty Kruzel-Davila
Karl Skorecki
author_facet Etty Kruzel-Davila
Karl Skorecki
author_sort Etty Kruzel-Davila
collection DOAJ
description Two gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease.
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spelling doaj.art-1987cfe30eef4d90928475e5c5eb2cdd2022-12-22T02:05:09ZengeLife Sciences Publications LtdeLife2050-084X2017-07-01610.7554/eLife.29056The double-edged sword of evolutionEtty Kruzel-Davila0https://orcid.org/0000-0002-7208-5707Karl Skorecki1https://orcid.org/0000-0002-0900-3406Department of Nephrology, Rambam Health Care Campus, Haifa, IsraelDepartment of Medical and Research Development, Rambam Heath Care Campus, Haifa, Israel; Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, IsraelTwo gene variants provide different levels of protection against sleeping sickness, but this comes with an increased risk of developing chronic kidney disease.https://elifesciences.org/articles/29056Trypanosoma bruceichronic kidney diseaseHuman African Trypanosomiasissleeping sicknessTrypanosoma brucei gambienseTrypanosoma brucei rhodesiense
spellingShingle Etty Kruzel-Davila
Karl Skorecki
The double-edged sword of evolution
eLife
Trypanosoma brucei
chronic kidney disease
Human African Trypanosomiasis
sleeping sickness
Trypanosoma brucei gambiense
Trypanosoma brucei rhodesiense
title The double-edged sword of evolution
title_full The double-edged sword of evolution
title_fullStr The double-edged sword of evolution
title_full_unstemmed The double-edged sword of evolution
title_short The double-edged sword of evolution
title_sort double edged sword of evolution
topic Trypanosoma brucei
chronic kidney disease
Human African Trypanosomiasis
sleeping sickness
Trypanosoma brucei gambiense
Trypanosoma brucei rhodesiense
url https://elifesciences.org/articles/29056
work_keys_str_mv AT ettykruzeldavila thedoubleedgedswordofevolution
AT karlskorecki thedoubleedgedswordofevolution
AT ettykruzeldavila doubleedgedswordofevolution
AT karlskorecki doubleedgedswordofevolution