A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis.
All skeletal muscle progenitor cells in the body derive from the dermomyotome, the dorsal epithelial domain of developing somites. These multipotent stem cells express Pax3, and this expression is maintained in the myogenic lineage where Pax3 plays an important role. Identification of Pax3 targets i...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-04-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2848553?pdf=render |