Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson Effect
The essential target of the tumor’s treatment is how to destroy its tissues. This work is dealing with the thermal damage of the tumor tissue due to the thermoelectrical effect based on the Thomson effect. The governing equation of tumor tissue in concentric spherical space based on the thermal lagg...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Mathematics |
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| Online Access: | https://www.mdpi.com/2227-7390/8/9/1488 |
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| author | Hamdy M. Youssef Alaa A. El-Bary |
| author_facet | Hamdy M. Youssef Alaa A. El-Bary |
| author_sort | Hamdy M. Youssef |
| collection | DOAJ |
| description | The essential target of the tumor’s treatment is how to destroy its tissues. This work is dealing with the thermal damage of the tumor tissue due to the thermoelectrical effect based on the Thomson effect. The governing equation of tumor tissue in concentric spherical space based on the thermal lagging effect is constructed and solved when the surface of the tumor tissue is subjected to a specific electric voltage. Different voltage and resistance effects have been studied and discussed for three different types of tumor tissues. The thermal damage quantity has been calculated with varying values of voltages and times. The voltage has significant effects on the temperature and the amount of the irreversible thermal damage of the tumor. Electrotherapy is a successful treatment. This work introduces a different model to doctors who work in clinical cancer to do experiments using electricity to damage the cancer cells. |
| first_indexed | 2024-03-10T16:36:32Z |
| format | Article |
| id | doaj.art-198df80f850841c3a2d8cd11ed7bb8f5 |
| institution | Directory Open Access Journal |
| issn | 2227-7390 |
| language | English |
| last_indexed | 2024-03-10T16:36:32Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Mathematics |
| spelling | doaj.art-198df80f850841c3a2d8cd11ed7bb8f52023-11-20T12:23:32ZengMDPI AGMathematics2227-73902020-09-0189148810.3390/math8091488Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson EffectHamdy M. Youssef0Alaa A. El-Bary1Mechanical Engineering Department, College of Engineering and Islamic Architecture, Umm Al-Qura University, PO Box 16222, Makkah, Saudi ArabiaBasic and Applied Science Institute, Arab Academy for Science, Technology, and Maritime Transport, P.O. Box 1029, Alexandria, EgyptThe essential target of the tumor’s treatment is how to destroy its tissues. This work is dealing with the thermal damage of the tumor tissue due to the thermoelectrical effect based on the Thomson effect. The governing equation of tumor tissue in concentric spherical space based on the thermal lagging effect is constructed and solved when the surface of the tumor tissue is subjected to a specific electric voltage. Different voltage and resistance effects have been studied and discussed for three different types of tumor tissues. The thermal damage quantity has been calculated with varying values of voltages and times. The voltage has significant effects on the temperature and the amount of the irreversible thermal damage of the tumor. Electrotherapy is a successful treatment. This work introduces a different model to doctors who work in clinical cancer to do experiments using electricity to damage the cancer cells.https://www.mdpi.com/2227-7390/8/9/1488electrotherapythermal laggingthermal damagetumor tissueThomson effect |
| spellingShingle | Hamdy M. Youssef Alaa A. El-Bary Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson Effect Mathematics electrotherapy thermal lagging thermal damage tumor tissue Thomson effect |
| title | Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson Effect |
| title_full | Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson Effect |
| title_fullStr | Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson Effect |
| title_full_unstemmed | Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson Effect |
| title_short | Voltage and Time Required for Irreversible Thermal Damage of Tumor Tissues during Electrochemotherapy under Thomson Effect |
| title_sort | voltage and time required for irreversible thermal damage of tumor tissues during electrochemotherapy under thomson effect |
| topic | electrotherapy thermal lagging thermal damage tumor tissue Thomson effect |
| url | https://www.mdpi.com/2227-7390/8/9/1488 |
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