IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function

IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function

Summary: Canonical interleukin-2 (IL-2) signaling via the high-affinity CD25-containing IL-2 receptor-Janus kinase (JAK)1,3-signal transducer and activator of transcription 5 (STAT5) pathway is essential for development and maintenance of CD4+CD25HiFoxp3+ regulatory T cells (Tregs) that support immu...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Hao Sun, Ho-Sup Lee, Sarah Hyun-Ji Kim, Mikhael Fernandes de Lima, Alexandre R. Gingras, Qinyi Du, Wilma McLaughlin, Jailail Ablack, Miguel A. Lopez-Ramirez, Frederic Lagarrigue, Zhichao Fan, John T. Chang, Derek VanDyke, Jamie B. Spangler, Mark H. Ginsberg
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Elsevier 2023-08-01
Цуврал:Cell Reports
Нөхцлүүд:
CP: Immunology
Онлайн хандалт:http://www.sciencedirect.com/science/article/pii/S2211124723010070

Интернэт

http://www.sciencedirect.com/science/article/pii/S2211124723010070

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