Intranasal HBsAg/HBcAg-Containing Vaccine Induces Neutralizing Anti-HBs Production in Hepatitis B Vaccine Non-Responders

Intranasal HBsAg/HBcAg-Containing Vaccine Induces Neutralizing Anti-HBs Production in Hepatitis B Vaccine Non-Responders

Hepatitis B vaccine induces the production of antibodies against hepatitis B surface antigen (anti-HBs) and prevents hepatitis B virus (HBV) infection. However, 5–10% of individuals cannot develop anti-HBs even after multiple vaccinations (HB vaccine non-responders). We developed an intranasal vacci...

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Bibliographic Details
Main Authors:	Kana Shiraishi, Osamu Yoshida, Yusuke Imai, Sheikh Mohammad Fazle Akbar, Takahiro Sanada, Michinori Kohara, Takashi Miyazaki, Taizou Kamishita, Teruki Miyake, Masashi Hirooka, Yoshio Tokumoto, Masanori Abe, Julio Cesar Aguilar Rubido, Gerardo Guillen Nieto, Yoichi Hiasa
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	Vaccines
Subjects:	hepatitis B virus cellular immunity immunoglobulin A infectious disease carboxyl vinyl polymer
Online Access:	https://www.mdpi.com/2076-393X/11/9/1479

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