DBS in Treatment of Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition for which pharmacological therapy is not always solvable. Various treatments have been suggested and deep brain stimulation (DBS) is currently under investigation for patients affected by PTSD. We review the neurocircuitry...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-01-01
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| Series: | Brain Sciences |
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| Online Access: | http://www.mdpi.com/2076-3425/8/1/18 |
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| author | Angelo Lavano Giusy Guzzi Attilio Della Torre Serena Marianna Lavano Raffaele Tiriolo Giorgio Volpentesta |
| author_facet | Angelo Lavano Giusy Guzzi Attilio Della Torre Serena Marianna Lavano Raffaele Tiriolo Giorgio Volpentesta |
| author_sort | Angelo Lavano |
| collection | DOAJ |
| description | Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition for which pharmacological therapy is not always solvable. Various treatments have been suggested and deep brain stimulation (DBS) is currently under investigation for patients affected by PTSD. We review the neurocircuitry and up-to-date clinical concepts which are behind the use of DBS in posttraumatic stress disorder (PTSD). The role of DBS in treatment-refractory PTSD patients has been investigated relying on both preclinical and clinical studies. DBS for PTSD is in its preliminary phases and likely to provide hope for patients with medical refractory PTSD following the results of randomized controlled studies. |
| first_indexed | 2024-12-11T14:07:51Z |
| format | Article |
| id | doaj.art-1991f4c009014109b8b40033607ae43b |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-12-11T14:07:51Z |
| publishDate | 2018-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-1991f4c009014109b8b40033607ae43b2022-12-22T01:03:34ZengMDPI AGBrain Sciences2076-34252018-01-01811810.3390/brainsci8010018brainsci8010018DBS in Treatment of Post-Traumatic Stress DisorderAngelo Lavano0Giusy Guzzi1Attilio Della Torre2Serena Marianna Lavano3Raffaele Tiriolo4Giorgio Volpentesta5Unit of Functional and Stereotactic Neurosurgery/Operative Unit of Neurosurgery, Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro 88100, ItalyUnit of Functional and Stereotactic Neurosurgery/Operative Unit of Neurosurgery, Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro 88100, ItalyUnit of Functional and Stereotactic Neurosurgery/Operative Unit of Neurosurgery, Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro 88100, ItalyDepartment of Health Science, University Magna Graecia of Catanzaro, Catanzaro 88100, ItalyUnit of Functional and Stereotactic Neurosurgery/Operative Unit of Neurosurgery, Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro 88100, ItalyUnit of Functional and Stereotactic Neurosurgery/Operative Unit of Neurosurgery, Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro 88100, ItalyPost-traumatic stress disorder (PTSD) is a debilitating psychiatric condition for which pharmacological therapy is not always solvable. Various treatments have been suggested and deep brain stimulation (DBS) is currently under investigation for patients affected by PTSD. We review the neurocircuitry and up-to-date clinical concepts which are behind the use of DBS in posttraumatic stress disorder (PTSD). The role of DBS in treatment-refractory PTSD patients has been investigated relying on both preclinical and clinical studies. DBS for PTSD is in its preliminary phases and likely to provide hope for patients with medical refractory PTSD following the results of randomized controlled studies.http://www.mdpi.com/2076-3425/8/1/18posttraumatic stress disorderdeep brain stimulationfear extinctionamygdalaprefrontal cortex |
| spellingShingle | Angelo Lavano Giusy Guzzi Attilio Della Torre Serena Marianna Lavano Raffaele Tiriolo Giorgio Volpentesta DBS in Treatment of Post-Traumatic Stress Disorder Brain Sciences posttraumatic stress disorder deep brain stimulation fear extinction amygdala prefrontal cortex |
| title | DBS in Treatment of Post-Traumatic Stress Disorder |
| title_full | DBS in Treatment of Post-Traumatic Stress Disorder |
| title_fullStr | DBS in Treatment of Post-Traumatic Stress Disorder |
| title_full_unstemmed | DBS in Treatment of Post-Traumatic Stress Disorder |
| title_short | DBS in Treatment of Post-Traumatic Stress Disorder |
| title_sort | dbs in treatment of post traumatic stress disorder |
| topic | posttraumatic stress disorder deep brain stimulation fear extinction amygdala prefrontal cortex |
| url | http://www.mdpi.com/2076-3425/8/1/18 |
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