Placental surface area mediates the association between FGFR2 methylation in placenta and full-term low birth weight in girls

Placental surface area mediates the association between FGFR2 methylation in placenta and full-term low birth weight in girls

Abstract Background Fibroblast growth factor receptor 2 (FGFR2) gene encodes a protein of the fibroblast growth factor receptor family. FGFR2 gene expression is associated with the regulation of implantation process of placenta which plays a vital role in fetal growth. DNA methylation is widely know...

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Bibliographic Details
Main Authors: Fu-Ying Tian, Xi-Meng Wang, Chuanbo Xie, Bo Zhao, Zhongzheng Niu, Lijun Fan, Marie-France Hivert, Wei-Qing Chen
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Clinical Epigenetics
Subjects:
FGFR2
DNA methylation
Placental surface area
Low birth weight
Mediation effect
Online Access:http://link.springer.com/article/10.1186/s13148-018-0472-5

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