Prostaglandin E2 contributes to L. braziliensis survival and therapeutic failure in cutaneous leishmaniasis

Prostaglandin E2 contributes to L. braziliensis survival and therapeutic failure in cutaneous leishmaniasis

Patients with cutaneous leishmaniasis (CL) present an exacerbated inflammatory response associated with tissue damage and ulcer development. In recent years, higher rates of failure to pentavalent antimoniate therapy have been observed, yet the underlying reason remains poorly understood. We hypothe...

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Bibliographic Details
Main Authors: Maurício T. Nascimento, Débora L. Viana, Fábio C. Peixoto, Sérgio M. Arruda, Edgar M. Carvalho, Lucas P. Carvalho
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
Cutaneous leishmaniasis
PGE2
therapeutic failure
L. braziliensis
inflammation
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2261565

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