The Modulatory Effects of DMF on Microglia in Aged Mice Are Sex-Specific

The Modulatory Effects of DMF on Microglia in Aged Mice Are Sex-Specific

There is a striking sex-related difference in the prevalence of many neurodegenerative diseases, highlighting the need to consider whether treatments may exert sex-specific effects. A change in microglial activation state is a common feature of several neurodegenerative diseases and is considered to...

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Bibliographic Details
Main Authors: Virginia Mela, Aline Sayd Gaban, Eoin O’Neill, Sibylle Bechet, Aífe Walsh, Marina A. Lynch
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
sexual dimorphism
age
microglia
inflammation
metabolism
dimethyl fumarate
Online Access:https://www.mdpi.com/2073-4409/11/4/729

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