Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors

Surface plasmon resonance (SPR) sensing is a well-established high-sensitivity, label-free and real-time detection technique for biomolecular interaction study. Its primary working principle consists of the measurement of the optical refractive index of the medium that is in close vicinity of the se...

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Main Authors: Sivaramakrishnan Ganesan, Sophie Maricot, Jean-Francois Robillard, Etienne Okada, Mohamed-Taieb Bakouche, Laurent Hay, Jean-Pierre Vilcot
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/21/6/2035
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author Sivaramakrishnan Ganesan
Sophie Maricot
Jean-Francois Robillard
Etienne Okada
Mohamed-Taieb Bakouche
Laurent Hay
Jean-Pierre Vilcot
author_facet Sivaramakrishnan Ganesan
Sophie Maricot
Jean-Francois Robillard
Etienne Okada
Mohamed-Taieb Bakouche
Laurent Hay
Jean-Pierre Vilcot
author_sort Sivaramakrishnan Ganesan
collection DOAJ
description Surface plasmon resonance (SPR) sensing is a well-established high-sensitivity, label-free and real-time detection technique for biomolecular interaction study. Its primary working principle consists of the measurement of the optical refractive index of the medium that is in close vicinity of the sensor surface. Bio-functionalization techniques allow biomolecular events to be located in such a way. Since optical refractive indices of any medium varies with the temperature, the place where the measurement takes place shall be within a temperature-controlled environment in order to ensure any temperature fluctuation is interpreted as a biomolecular event. Since the SPR measurement probes the sensed medium within the penetration depth of the plasmonic wave, which is less or in the order of 1 µm, we propose to use the metallic film constituting the detection surface as a localized heater aiming at controlling finely and quickly the temperature of the sensed medium. The Joule heating principle is then used and the modeling of the heater is reported as well as its validation by thermal IR imaging. Using water as a demonstration medium, SPR measurement results at different temperatures are successfully compared to the theoretical optical refractive index of water versus temperature.
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spelling doaj.art-1999d9c0e7bd4b96b0b263adf70f74c42023-11-21T10:22:07ZengMDPI AGSensors1424-82202021-03-01216203510.3390/s21062035Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based SensorsSivaramakrishnan Ganesan0Sophie Maricot1Jean-Francois Robillard2Etienne Okada3Mohamed-Taieb Bakouche4Laurent Hay5Jean-Pierre Vilcot6Univ. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, Junia, UMR 8520—IEMN, F-59000 Lille, FranceUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, Junia, UMR 8520—IEMN, F-59000 Lille, FranceUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, Junia, UMR 8520—IEMN, F-59000 Lille, FranceUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, Junia, UMR 8520—IEMN, F-59000 Lille, FranceUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, Junia, UMR 8520—IEMN, F-59000 Lille, FranceUniv. Lille, CNRS, UMR8523-PhLAM-Physique des Lasers Atomes et Molécules, CERLA/IRCICA, F-59000 Lille, FranceUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, Junia, UMR 8520—IEMN, F-59000 Lille, FranceSurface plasmon resonance (SPR) sensing is a well-established high-sensitivity, label-free and real-time detection technique for biomolecular interaction study. Its primary working principle consists of the measurement of the optical refractive index of the medium that is in close vicinity of the sensor surface. Bio-functionalization techniques allow biomolecular events to be located in such a way. Since optical refractive indices of any medium varies with the temperature, the place where the measurement takes place shall be within a temperature-controlled environment in order to ensure any temperature fluctuation is interpreted as a biomolecular event. Since the SPR measurement probes the sensed medium within the penetration depth of the plasmonic wave, which is less or in the order of 1 µm, we propose to use the metallic film constituting the detection surface as a localized heater aiming at controlling finely and quickly the temperature of the sensed medium. The Joule heating principle is then used and the modeling of the heater is reported as well as its validation by thermal IR imaging. Using water as a demonstration medium, SPR measurement results at different temperatures are successfully compared to the theoretical optical refractive index of water versus temperature.https://www.mdpi.com/1424-8220/21/6/2035surface plasmon resonanceplasmonic sensortemperature controllocalized heating
spellingShingle Sivaramakrishnan Ganesan
Sophie Maricot
Jean-Francois Robillard
Etienne Okada
Mohamed-Taieb Bakouche
Laurent Hay
Jean-Pierre Vilcot
Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors
Sensors
surface plasmon resonance
plasmonic sensor
temperature control
localized heating
title Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors
title_full Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors
title_fullStr Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors
title_full_unstemmed Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors
title_short Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors
title_sort plasmonic layer as a localized temperature control element for surface plasmonic resonance based sensors
topic surface plasmon resonance
plasmonic sensor
temperature control
localized heating
url https://www.mdpi.com/1424-8220/21/6/2035
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AT jeanfrancoisrobillard plasmoniclayerasalocalizedtemperaturecontrolelementforsurfaceplasmonicresonancebasedsensors
AT etienneokada plasmoniclayerasalocalizedtemperaturecontrolelementforsurfaceplasmonicresonancebasedsensors
AT mohamedtaiebbakouche plasmoniclayerasalocalizedtemperaturecontrolelementforsurfaceplasmonicresonancebasedsensors
AT laurenthay plasmoniclayerasalocalizedtemperaturecontrolelementforsurfaceplasmonicresonancebasedsensors
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