Aptamers Binding to c-Met Inhibiting Tumor Cell Migration.

Aptamers Binding to c-Met Inhibiting Tumor Cell Migration.

The human receptor tyrosine kinase c-Met plays an important role in the control of critical cellular processes. Since c-Met is frequently over expressed or deregulated in human malignancies, blocking its activation is of special interest for therapy. In normal conditions, the c-Met receptor is activ...

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Bibliographic Details
Main Authors: Birgit Piater, Achim Doerner, Ralf Guenther, Harald Kolmar, Bjoern Hock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0142412&type=printable

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