Polymorphisms Within DNA Double-Strand Breaks Repair-Related Genes Contribute to Structural Chromosome Abnormality in Recurrent Pregnancy Loss

Polymorphisms Within DNA Double-Strand Breaks Repair-Related Genes Contribute to Structural Chromosome Abnormality in Recurrent Pregnancy Loss

Background: Structural chromosome abnormality (SCA) is an important cause of human diseases, including recurrent pregnancy loss (RPL). DNA double-strand breaks (DSBs) repair-related genes play critical roles in SCA. The present study aims to investigate the potential contribution of DSBs repair-rela...

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Bibliographic Details
Main Authors:	Zhenbo Cheng, Dehua Cheng, Jiancheng Li, Lihuang Guo, Wei Zhang, Conghui Zhang, Yangxu Liu, Yue Huang, Keqian Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Series:	Frontiers in Genetics
Subjects:	structural chromosome abnormalities gene polymorphisms DNA double-strand breaks non-homologous end joining EP300 whole-exome sequencing
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.787718/full

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