Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations
In nature, many enzymes are attached or inserted into the cell membrane, having hydrophobic subunits or lipid chains for this purpose. Their reconstitution on electrodes maintaining their natural structural characteristics allows for optimizing their electrocatalytic properties and stability. Differ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/20/12/3393 |
| _version_ | 1827714959870525440 |
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| author | Julia Alvarez-Malmagro Gabriel García-Molina Antonio López De Lacey |
| author_facet | Julia Alvarez-Malmagro Gabriel García-Molina Antonio López De Lacey |
| author_sort | Julia Alvarez-Malmagro |
| collection | DOAJ |
| description | In nature, many enzymes are attached or inserted into the cell membrane, having hydrophobic subunits or lipid chains for this purpose. Their reconstitution on electrodes maintaining their natural structural characteristics allows for optimizing their electrocatalytic properties and stability. Different biomimetic strategies have been developed for modifying electrodes surfaces to accommodate membrane-bound enzymes, including the formation of self-assembled monolayers of hydrophobic compounds, lipid bilayers, or liposomes deposition. An overview of the different strategies used for the formation of biomimetic membranes, the reconstitution of membrane enzymes on electrodes, and their applications as biosensors is presented. |
| first_indexed | 2024-03-10T19:07:46Z |
| format | Article |
| id | doaj.art-19a806158b844f659d3293b2b360e30d |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T19:07:46Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-19a806158b844f659d3293b2b360e30d2023-11-20T03:58:47ZengMDPI AGSensors1424-82202020-06-012012339310.3390/s20123393Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic ConfigurationsJulia Alvarez-Malmagro0Gabriel García-Molina1Antonio López De Lacey2Instituto de Catálisis y Petroleoquímica, CSIC, c/Marie Curie 2, 28049 Madrid, SpainInstituto de Catálisis y Petroleoquímica, CSIC, c/Marie Curie 2, 28049 Madrid, SpainInstituto de Catálisis y Petroleoquímica, CSIC, c/Marie Curie 2, 28049 Madrid, SpainIn nature, many enzymes are attached or inserted into the cell membrane, having hydrophobic subunits or lipid chains for this purpose. Their reconstitution on electrodes maintaining their natural structural characteristics allows for optimizing their electrocatalytic properties and stability. Different biomimetic strategies have been developed for modifying electrodes surfaces to accommodate membrane-bound enzymes, including the formation of self-assembled monolayers of hydrophobic compounds, lipid bilayers, or liposomes deposition. An overview of the different strategies used for the formation of biomimetic membranes, the reconstitution of membrane enzymes on electrodes, and their applications as biosensors is presented.https://www.mdpi.com/1424-8220/20/12/3393biosensorbiomimetic membranesmembrane-bound enzymeselectrodes |
| spellingShingle | Julia Alvarez-Malmagro Gabriel García-Molina Antonio López De Lacey Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations Sensors biosensor biomimetic membranes membrane-bound enzymes electrodes |
| title | Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations |
| title_full | Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations |
| title_fullStr | Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations |
| title_full_unstemmed | Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations |
| title_short | Electrochemical Biosensors Based on Membrane-Bound Enzymes in Biomimetic Configurations |
| title_sort | electrochemical biosensors based on membrane bound enzymes in biomimetic configurations |
| topic | biosensor biomimetic membranes membrane-bound enzymes electrodes |
| url | https://www.mdpi.com/1424-8220/20/12/3393 |
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