Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infections
During the last decade, the advent of multi-drug resistant pathogens responsible for skin infections tends to make conventional treatments obsolete. Even though many studies have reported the antimicrobial properties of essential oils (EOs), the inconsistent use of various susceptibility testing met...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-03-01
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| Series: | Scientific African |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468227621000107 |
| _version_ | 1818624523243618304 |
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| author | Hope T Sounouvou Habib Toukourou Lucy Catteau Fatiou Toukourou Brigitte Evrard Françoise Van Bambeke Fernand Gbaguidi Joëlle Quetin-Leclercq |
| author_facet | Hope T Sounouvou Habib Toukourou Lucy Catteau Fatiou Toukourou Brigitte Evrard Françoise Van Bambeke Fernand Gbaguidi Joëlle Quetin-Leclercq |
| author_sort | Hope T Sounouvou |
| collection | DOAJ |
| description | During the last decade, the advent of multi-drug resistant pathogens responsible for skin infections tends to make conventional treatments obsolete. Even though many studies have reported the antimicrobial properties of essential oils (EOs), the inconsistent use of various susceptibility testing methods has made information on antimicrobial potential of many EO varieties fragmentary. Using a single method approach, the objective of this work was to assess and to compare the antibacterial and antifungal properties, against skin pathogens, of EOs extracted from West African aromatic plants.Twenty-three plant samples collected in Benin and Burkina Faso were screened against 20 bacterial and fungal isolates obtained from skin lesions. Activity was evaluated by the determination of minimal inhibitory concentrations (MICs), with readings facilitated by the use of resazurin, a blue dye metabolized into pink resorufin by viable cells.Following this screening, nine EOs were found particularly active with MICs lower than 0.35% v/v. Gas Chromatography-Mass Spectrometry (GC/MS) analysis was used to determine the phytochemical profile of these active EOs which were found exceptionally rich in oxygenated monoterpenes, especially aldehydes, alcohols or phenols and their derivatives.Through this study, we demonstrated that several West African EOs have a significant antimicrobial potential which could, however, be considerably impacted by plant growing or harvesting place due to phytochemical composition variation. These EOs, even if their antimicrobial effects appeared lower than those of conventional antibiotics, constitute easily available mixtures of active compounds and could nevertheless be considered, in the context of increasing multidrug resistance, as complementary or alternative therapies in common skin infections management. |
| first_indexed | 2024-12-16T18:58:18Z |
| format | Article |
| id | doaj.art-19a91918f44b4469a6841acfe9a90857 |
| institution | Directory Open Access Journal |
| issn | 2468-2276 |
| language | English |
| last_indexed | 2024-12-16T18:58:18Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Scientific African |
| spelling | doaj.art-19a91918f44b4469a6841acfe9a908572022-12-21T22:20:28ZengElsevierScientific African2468-22762021-03-0111e00706Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infectionsHope T Sounouvou0Habib Toukourou1Lucy Catteau2Fatiou Toukourou3Brigitte Evrard4Françoise Van Bambeke5Fernand Gbaguidi6Joëlle Quetin-Leclercq7Laboratory of Pharmaceutical Technology and Biopharmacy, CIRM, University of Liège, 4000 Liège, Belgium; Medicinal Organic Chemistry Laboratory (MOCL), School of Pharmacy, Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Campus du Champ de Foire, Cotonou, Bénin; Pharmacognosy (GNOS), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, 1200 Brussels, Belgium; Corresponding author.Medicinal Organic Chemistry Laboratory (MOCL), School of Pharmacy, Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Campus du Champ de Foire, Cotonou, Bénin; Pharmacognosy (GNOS), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, 1200 Brussels, BelgiumPharmacognosy (GNOS), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, 1200 Brussels, BelgiumLaboratoire de Microbiologie et des Technologies Alimentaires, Champ de Foire ISBA, Faculté des Sciences et Techniques, Université d'Abomey-Calavi, Cotonou BP 526, BéninLaboratory of Pharmaceutical Technology and Biopharmacy, CIRM, University of Liège, 4000 Liège, BelgiumPharmacologie cellulaire et moléculaire (FACM), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, 1200 Brussels, BelgiumMedicinal Organic Chemistry Laboratory (MOCL), School of Pharmacy, Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Campus du Champ de Foire, Cotonou, BéninPharmacognosy (GNOS), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, 1200 Brussels, BelgiumDuring the last decade, the advent of multi-drug resistant pathogens responsible for skin infections tends to make conventional treatments obsolete. Even though many studies have reported the antimicrobial properties of essential oils (EOs), the inconsistent use of various susceptibility testing methods has made information on antimicrobial potential of many EO varieties fragmentary. Using a single method approach, the objective of this work was to assess and to compare the antibacterial and antifungal properties, against skin pathogens, of EOs extracted from West African aromatic plants.Twenty-three plant samples collected in Benin and Burkina Faso were screened against 20 bacterial and fungal isolates obtained from skin lesions. Activity was evaluated by the determination of minimal inhibitory concentrations (MICs), with readings facilitated by the use of resazurin, a blue dye metabolized into pink resorufin by viable cells.Following this screening, nine EOs were found particularly active with MICs lower than 0.35% v/v. Gas Chromatography-Mass Spectrometry (GC/MS) analysis was used to determine the phytochemical profile of these active EOs which were found exceptionally rich in oxygenated monoterpenes, especially aldehydes, alcohols or phenols and their derivatives.Through this study, we demonstrated that several West African EOs have a significant antimicrobial potential which could, however, be considerably impacted by plant growing or harvesting place due to phytochemical composition variation. These EOs, even if their antimicrobial effects appeared lower than those of conventional antibiotics, constitute easily available mixtures of active compounds and could nevertheless be considered, in the context of increasing multidrug resistance, as complementary or alternative therapies in common skin infections management.http://www.sciencedirect.com/science/article/pii/S2468227621000107Essential oilsSkin infectionsMICBacteriaYeasts |
| spellingShingle | Hope T Sounouvou Habib Toukourou Lucy Catteau Fatiou Toukourou Brigitte Evrard Françoise Van Bambeke Fernand Gbaguidi Joëlle Quetin-Leclercq Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infections Scientific African Essential oils Skin infections MIC Bacteria Yeasts |
| title | Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infections |
| title_full | Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infections |
| title_fullStr | Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infections |
| title_full_unstemmed | Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infections |
| title_short | Antimicrobial potentials of essential oils extracted from West African aromatic plants on common skin infections |
| title_sort | antimicrobial potentials of essential oils extracted from west african aromatic plants on common skin infections |
| topic | Essential oils Skin infections MIC Bacteria Yeasts |
| url | http://www.sciencedirect.com/science/article/pii/S2468227621000107 |
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