Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration
We present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The Janus hydrogel microbeads, that consist of fluorescent glucose and pH sensors, were fabricated with a UV-assisted centrifugal microfluidic device. The microbead can calibrate the pH values of its...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/21/14/4829 |
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| author | Maru Ando Mio Tsuchiya Shun Itai Tomomi Murayama Yuta Kurashina Yun Jung Heo Hiroaki Onoe |
| author_facet | Maru Ando Mio Tsuchiya Shun Itai Tomomi Murayama Yuta Kurashina Yun Jung Heo Hiroaki Onoe |
| author_sort | Maru Ando |
| collection | DOAJ |
| description | We present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The Janus hydrogel microbeads, that consist of fluorescent glucose and pH sensors, were fabricated with a UV-assisted centrifugal microfluidic device. The microbead can calibrate the pH values of its surroundings and enables accurate measurements of glucose within various pH conditions. As a proof of concept, we succeeded in obtaining the accurate value of glucose concentration in a body-fluid-like sample solution. We believe that our fluorescent microbeads, with pH calibration capability, could be applied to fully implantable sensors for continuous glucose monitoring. |
| first_indexed | 2024-03-10T09:23:24Z |
| format | Article |
| id | doaj.art-19a96ca328b94f0498de8c9915740811 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T09:23:24Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-19a96ca328b94f0498de8c99157408112023-11-22T04:56:40ZengMDPI AGSensors1424-82202021-07-012114482910.3390/s21144829Janus Hydrogel Microbeads for Glucose Sensing with pH CalibrationMaru Ando0Mio Tsuchiya1Shun Itai2Tomomi Murayama3Yuta Kurashina4Yun Jung Heo5Hiroaki Onoe6Westminster School, London SW1P 3PB, UKDepartment of Mechanical Engineering, Faculty of Science and Technology, Keio University, Kanagawa 223-8522, JapanDepartment of Mechanical Engineering, Faculty of Science and Technology, Keio University, Kanagawa 223-8522, JapanDepartment of Mechanical Engineering, Faculty of Science and Technology, Keio University, Kanagawa 223-8522, JapanDepartment of Mechanical Engineering, Faculty of Science and Technology, Keio University, Kanagawa 223-8522, JapanDepartment of Mechanical Engineering, Collage of Engineering, Kyung Hee University, Yongin 17104, KoreaDepartment of Mechanical Engineering, Faculty of Science and Technology, Keio University, Kanagawa 223-8522, JapanWe present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The Janus hydrogel microbeads, that consist of fluorescent glucose and pH sensors, were fabricated with a UV-assisted centrifugal microfluidic device. The microbead can calibrate the pH values of its surroundings and enables accurate measurements of glucose within various pH conditions. As a proof of concept, we succeeded in obtaining the accurate value of glucose concentration in a body-fluid-like sample solution. We believe that our fluorescent microbeads, with pH calibration capability, could be applied to fully implantable sensors for continuous glucose monitoring.https://www.mdpi.com/1424-8220/21/14/4829glucose sensorglucose monitoringpH calibrationhydrogelJanus particle |
| spellingShingle | Maru Ando Mio Tsuchiya Shun Itai Tomomi Murayama Yuta Kurashina Yun Jung Heo Hiroaki Onoe Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration Sensors glucose sensor glucose monitoring pH calibration hydrogel Janus particle |
| title | Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration |
| title_full | Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration |
| title_fullStr | Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration |
| title_full_unstemmed | Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration |
| title_short | Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration |
| title_sort | janus hydrogel microbeads for glucose sensing with ph calibration |
| topic | glucose sensor glucose monitoring pH calibration hydrogel Janus particle |
| url | https://www.mdpi.com/1424-8220/21/14/4829 |
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