COVID-19 trials: declarations of data sharing intentions at trial registration and at publication
Abstract Background The sharing of individual participant-level data from COVID-19 trials would allow re-use and secondary analysis that can help accelerate the identification of effective treatments. The sharing of trial data is not the norm, but the unprecedented pandemic caused by SARS-CoV-2 may...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-02-01
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| Series: | Trials |
| Online Access: | https://doi.org/10.1186/s13063-021-05104-z |
| _version_ | 1819283780550000640 |
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| author | Rebecca Li Megan von Isenburg Marcia Levenstein Stan Neumann Julie Wood Ida Sim |
| author_facet | Rebecca Li Megan von Isenburg Marcia Levenstein Stan Neumann Julie Wood Ida Sim |
| author_sort | Rebecca Li |
| collection | DOAJ |
| description | Abstract Background The sharing of individual participant-level data from COVID-19 trials would allow re-use and secondary analysis that can help accelerate the identification of effective treatments. The sharing of trial data is not the norm, but the unprecedented pandemic caused by SARS-CoV-2 may serve as an impetus for greater data sharing. We sought to assess the data sharing intentions of interventional COVID-19 trials as declared in trial registrations and publications. Methods We searched ClinicalTrials.gov and PubMed for COVID-19 interventional trials. We analyzed responses to ClinicalTrials.gov fields regarding intent to share individual participant level data and analyzed the data sharing statements in eligible publications. Results Nine hundred twenty-four trial registrations were analyzed. 15.7% were willing to share, of which 38.6% were willing to share immediately upon publication of results. 47.6% declared they were not willing to share. Twenty-eight publications were analyzed representing 26 unique COVID-19 trials. Only seven publications contained data sharing statements; six indicated a willingness to share data whereas one indicated that data was not available for sharing. Conclusions At a time of pressing need for researchers to work together to combat a global pandemic, intent to share individual participant-level data from COVID-19 interventional trials is limited. |
| first_indexed | 2024-12-24T01:36:55Z |
| format | Article |
| id | doaj.art-19aae080d592480cbbb56851977ceb5d |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-12-24T01:36:55Z |
| publishDate | 2021-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-19aae080d592480cbbb56851977ceb5d2022-12-21T17:22:10ZengBMCTrials1745-62152021-02-012211510.1186/s13063-021-05104-zCOVID-19 trials: declarations of data sharing intentions at trial registration and at publicationRebecca Li0Megan von Isenburg1Marcia Levenstein2Stan Neumann3Julie Wood4Ida Sim5VivliDuke UniversityVivliVivliVivliVivliAbstract Background The sharing of individual participant-level data from COVID-19 trials would allow re-use and secondary analysis that can help accelerate the identification of effective treatments. The sharing of trial data is not the norm, but the unprecedented pandemic caused by SARS-CoV-2 may serve as an impetus for greater data sharing. We sought to assess the data sharing intentions of interventional COVID-19 trials as declared in trial registrations and publications. Methods We searched ClinicalTrials.gov and PubMed for COVID-19 interventional trials. We analyzed responses to ClinicalTrials.gov fields regarding intent to share individual participant level data and analyzed the data sharing statements in eligible publications. Results Nine hundred twenty-four trial registrations were analyzed. 15.7% were willing to share, of which 38.6% were willing to share immediately upon publication of results. 47.6% declared they were not willing to share. Twenty-eight publications were analyzed representing 26 unique COVID-19 trials. Only seven publications contained data sharing statements; six indicated a willingness to share data whereas one indicated that data was not available for sharing. Conclusions At a time of pressing need for researchers to work together to combat a global pandemic, intent to share individual participant-level data from COVID-19 interventional trials is limited.https://doi.org/10.1186/s13063-021-05104-z |
| spellingShingle | Rebecca Li Megan von Isenburg Marcia Levenstein Stan Neumann Julie Wood Ida Sim COVID-19 trials: declarations of data sharing intentions at trial registration and at publication Trials |
| title | COVID-19 trials: declarations of data sharing intentions at trial registration and at publication |
| title_full | COVID-19 trials: declarations of data sharing intentions at trial registration and at publication |
| title_fullStr | COVID-19 trials: declarations of data sharing intentions at trial registration and at publication |
| title_full_unstemmed | COVID-19 trials: declarations of data sharing intentions at trial registration and at publication |
| title_short | COVID-19 trials: declarations of data sharing intentions at trial registration and at publication |
| title_sort | covid 19 trials declarations of data sharing intentions at trial registration and at publication |
| url | https://doi.org/10.1186/s13063-021-05104-z |
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