Risk Factors for Malignancy in Patients with Multinodular Goiter
Introduction The identification of thyroid cancer may be conducted through clinical detection, imaging method, and histopathological examination. Both solitary nodules and multinodular goiter are associated with malignancy. Objective To assess the risk factors for malignancy among patient...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2023-01-01
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| Series: | International Archives of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1748925 |
| _version_ | 1797942179333668864 |
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| author | Guilherme Arruda Fernandes Leandro Luongo de Matos Rogério Aparecido Dedivitis |
| author_facet | Guilherme Arruda Fernandes Leandro Luongo de Matos Rogério Aparecido Dedivitis |
| author_sort | Guilherme Arruda Fernandes |
| collection | DOAJ |
| description | Introduction The identification of thyroid cancer may be conducted through clinical detection, imaging method, and histopathological examination. Both solitary nodules and multinodular goiter are associated with malignancy.
Objective To assess the risk factors for malignancy among patients with multinodular goiter submitted to total thyroidectomy.
Methods A series of 712 consecutive patients, submitted to total thyroidectomy between 2005 and 2016 with multinodular goiter regarding clinical, ultrasound, and pathological variables, was retrospectively evaluated.
Results There were 408 cases of papillary carcinoma (57.3%), with the remaining being benign. Gender had no statistical significance (p = 0.169) for malignancy, unlike the Bethesda index, higher age group (p = 0.005), shorter clinical history time (p = 0.036), smaller number of nodules (p < 0.0001), and smaller nodule size (p < 0.0001), which were related to malignancy.
Conclusion The Bethesda index, older age group, shorter clinical history, smaller number of nodules, and smaller size of nodule were related to the diagnosis of papillary carcinoma. |
| first_indexed | 2024-04-10T20:03:17Z |
| format | Article |
| id | doaj.art-19ac25cce9fa40acab447fb49891216c |
| institution | Directory Open Access Journal |
| issn | 1809-9777 1809-4864 |
| language | English |
| last_indexed | 2024-04-10T20:03:17Z |
| publishDate | 2023-01-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | International Archives of Otorhinolaryngology |
| spelling | doaj.art-19ac25cce9fa40acab447fb49891216c2023-01-26T23:53:45ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642023-01-012701e138e14210.1055/s-0042-1748925Risk Factors for Malignancy in Patients with Multinodular GoiterGuilherme Arruda Fernandes0Leandro Luongo de Matos1Rogério Aparecido Dedivitis2Faculdade de Ciências da Saúde, Universidade Metropolitana de Santos, Santos, SP, BrasilSurgery Department, Faculdade de Medicina da USP, São Paulo, SP, BrasilSurgery Department, Faculdade de Medicina da USP, São Paulo, SP, BrasilIntroduction The identification of thyroid cancer may be conducted through clinical detection, imaging method, and histopathological examination. Both solitary nodules and multinodular goiter are associated with malignancy. Objective To assess the risk factors for malignancy among patients with multinodular goiter submitted to total thyroidectomy. Methods A series of 712 consecutive patients, submitted to total thyroidectomy between 2005 and 2016 with multinodular goiter regarding clinical, ultrasound, and pathological variables, was retrospectively evaluated. Results There were 408 cases of papillary carcinoma (57.3%), with the remaining being benign. Gender had no statistical significance (p = 0.169) for malignancy, unlike the Bethesda index, higher age group (p = 0.005), shorter clinical history time (p = 0.036), smaller number of nodules (p < 0.0001), and smaller nodule size (p < 0.0001), which were related to malignancy. Conclusion The Bethesda index, older age group, shorter clinical history, smaller number of nodules, and smaller size of nodule were related to the diagnosis of papillary carcinoma.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1748925thyroid cancerthyroidectomycarcinomapapillary |
| spellingShingle | Guilherme Arruda Fernandes Leandro Luongo de Matos Rogério Aparecido Dedivitis Risk Factors for Malignancy in Patients with Multinodular Goiter International Archives of Otorhinolaryngology thyroid cancer thyroidectomy carcinoma papillary |
| title | Risk Factors for Malignancy in Patients with Multinodular Goiter |
| title_full | Risk Factors for Malignancy in Patients with Multinodular Goiter |
| title_fullStr | Risk Factors for Malignancy in Patients with Multinodular Goiter |
| title_full_unstemmed | Risk Factors for Malignancy in Patients with Multinodular Goiter |
| title_short | Risk Factors for Malignancy in Patients with Multinodular Goiter |
| title_sort | risk factors for malignancy in patients with multinodular goiter |
| topic | thyroid cancer thyroidectomy carcinoma papillary |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1748925 |
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