Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective Ventilation
Coronavirus disease (COVID-19) started in Wuhan (China) at the end of 2019, and then increased rapidly. In patients with severe acute respiratory distress syndrome (ARDS) caused by COVID-19, venovenous extracorporeal membrane oxygenation (VV-ECMO) is considered a rescue therapy that provides adequat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1010-660X/56/11/570 |
| _version_ | 1797727538574786560 |
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| author | Mi Hwa Park Ah Jin Kim Man-Jong Lee Young Sam Kim Jung Soo Kim |
| author_facet | Mi Hwa Park Ah Jin Kim Man-Jong Lee Young Sam Kim Jung Soo Kim |
| author_sort | Mi Hwa Park |
| collection | DOAJ |
| description | Coronavirus disease (COVID-19) started in Wuhan (China) at the end of 2019, and then increased rapidly. In patients with severe acute respiratory distress syndrome (ARDS) caused by COVID-19, venovenous extracorporeal membrane oxygenation (VV-ECMO) is considered a rescue therapy that provides adequate gas exchange. The way in which mechanical ventilation is applied during VV-ECMO is not clear, however it is associated with prognosis. Currently, the mortality rate of COVID-19 patients that receive VV-ECMO stands at approximately 50%. Here, we report three patients that successfully recovered from COVID-19-induced ARDS after VV-ECMO and implementation of an ultra-protective ventilation. This ventilation strategy involved maintaining a peak inspiratory pressure of ≤20 cmH<sub>2</sub>O and a positive end-expiratory pressure (PEEP) of ≤ 10 cmH<sub>2</sub>O, which are lower values than have been previously reported. Thus, we suggest that this ultra-protective ventilation be considered during VV-ECMO as it minimizes the ventilator-induced lung injury. |
| first_indexed | 2024-03-12T11:01:11Z |
| format | Article |
| id | doaj.art-19afd1a1f3a248e4a211ef241afaeec6 |
| institution | Directory Open Access Journal |
| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T11:01:11Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-19afd1a1f3a248e4a211ef241afaeec62023-09-02T05:30:58ZengMDPI AGMedicina1010-660X2020-10-015657057010.3390/medicina56110570Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective VentilationMi Hwa Park0Ah Jin Kim1Man-Jong Lee2Young Sam Kim3Jung Soo Kim4Division of Pulmonology, Department of Internal Medicine, Inha University Hospital, Incheon 22332, KoreaDivision of Critical Care Medicine, Department of Internal Medicine, Inha University Hospital, Incheon 22332, KoreaDivision of Critical Care Medicine, Department of Internal Medicine, Inha University Hospital, Incheon 22332, KoreaDivision of Thoracic Surgery, Inha University Hospital, Incheon 22332, KoreaDivision of Pulmonology, Department of Internal Medicine, Inha University Hospital, Incheon 22332, KoreaCoronavirus disease (COVID-19) started in Wuhan (China) at the end of 2019, and then increased rapidly. In patients with severe acute respiratory distress syndrome (ARDS) caused by COVID-19, venovenous extracorporeal membrane oxygenation (VV-ECMO) is considered a rescue therapy that provides adequate gas exchange. The way in which mechanical ventilation is applied during VV-ECMO is not clear, however it is associated with prognosis. Currently, the mortality rate of COVID-19 patients that receive VV-ECMO stands at approximately 50%. Here, we report three patients that successfully recovered from COVID-19-induced ARDS after VV-ECMO and implementation of an ultra-protective ventilation. This ventilation strategy involved maintaining a peak inspiratory pressure of ≤20 cmH<sub>2</sub>O and a positive end-expiratory pressure (PEEP) of ≤ 10 cmH<sub>2</sub>O, which are lower values than have been previously reported. Thus, we suggest that this ultra-protective ventilation be considered during VV-ECMO as it minimizes the ventilator-induced lung injury.https://www.mdpi.com/1010-660X/56/11/570COVID-19acute respiratory distress syndromevenovenous extracorporeal membrane oxygenationultra-protective ventilation |
| spellingShingle | Mi Hwa Park Ah Jin Kim Man-Jong Lee Young Sam Kim Jung Soo Kim Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective Ventilation Medicina COVID-19 acute respiratory distress syndrome venovenous extracorporeal membrane oxygenation ultra-protective ventilation |
| title | Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective Ventilation |
| title_full | Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective Ventilation |
| title_fullStr | Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective Ventilation |
| title_full_unstemmed | Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective Ventilation |
| title_short | Case Report of Patients with Acute Respiratory Distress Syndrome Caused by COVID-19: Successfully Treated by Venovenous Extracorporeal Membrane Oxygenation and an Ultra-Protective Ventilation |
| title_sort | case report of patients with acute respiratory distress syndrome caused by covid 19 successfully treated by venovenous extracorporeal membrane oxygenation and an ultra protective ventilation |
| topic | COVID-19 acute respiratory distress syndrome venovenous extracorporeal membrane oxygenation ultra-protective ventilation |
| url | https://www.mdpi.com/1010-660X/56/11/570 |
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