A comprehensive overview of mitochondrial DNA 4977-bp deletion in cancer studies

A comprehensive overview of mitochondrial DNA 4977-bp deletion in cancer studies

Mitochondria are cellular machines essential for energy production. The biogenesis of mitochondria is a highly complex and it depends on the coordination of the nuclear and mitochondrial genome. Mitochondrial DNA (mtDNA) mutations and deletions are suspected to be associated with carcinogenesis. The...

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Bibliographic Details
Main Authors: Abdul Aziz Mohamed Yusoff, Wan Salihah Wan Abdullah, Siti Zulaikha Nashwa Mohd Khair, Siti Muslihah Abd Radzak
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Oncology Reviews
Subjects:
Mitochondrial DNA (mtDNA) deletion
4977-bp mtDNA
cancer.
Online Access:https://oncologyreviews.org/index.php/or/article/view/409

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