Dynamic Editome of Zebrafish under Aminoglycosides Treatment and Its Potential Involvement in Ototoxicity

Dynamic Editome of Zebrafish under Aminoglycosides Treatment and Its Potential Involvement in Ototoxicity

RNA editing is an important co- and post-transcriptional event that generates RNA and protein diversity. Aminoglycosides are a group of bactericidal antibiotics and a mainstay of antimicrobial therapy for several life-threatening infections. However, aminoglycosides can induce ototoxicity, resulting...

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Bibliographic Details
Main Authors: Sijia Yan, Yulan Lu, Lin He, Xinzhi Zhao, Lihua Wu, Huizhong Zhu, Menglin Jiang, Yu Su, Wei Cao, Weidong Tian, Qinghe Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Pharmacology
Subjects:
zebrafish
RNA-editing
RNA-Seq
aminoglycosides (AG)
ototoxicity
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00854/full

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