The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Spirotetramat is a potential tetronic acid pesticide for controlling various pests with piercing–sucking mouthparts. To clarify its dietary risk on cabbage, we established an ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method and then investigated the residual...
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MDPI AG
2023-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/12/4763 |
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| author | Junli Cao Jindong Li Pengcheng Ren Yanli Qi Shu Qin |
| author_facet | Junli Cao Jindong Li Pengcheng Ren Yanli Qi Shu Qin |
| author_sort | Junli Cao |
| collection | DOAJ |
| description | Spirotetramat is a potential tetronic acid pesticide for controlling various pests with piercing–sucking mouthparts. To clarify its dietary risk on cabbage, we established an ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method and then investigated the residual levels of spirotetramat and its four metabolites in cabbage collected from field experiments under good agricultural practices (GAPs). The average recoveries of spirotetramat and its metabolites in cabbage were 74~110%, while the relative standard deviation (RSD) was 1~6%, and the limit of quantitation (LOQ) was 0.01 mg kg<sup>−1</sup>. The terminal residue of spirotetramat was in the range of <0.05~0.33 mg kg<sup>−1</sup>, the chronic dietary risk (RQ<sub>c</sub>) was 17.56%, and the acute dietary risk (RQ<sub>a</sub>) was 0.025~0.049%, which means an acceptable dietary intake risk. This study provides data to guide on the use of spirotetramat and to establish the maximum residue limits (MRLs) of spirotetramat on cabbage. |
| first_indexed | 2024-03-11T02:06:01Z |
| format | Article |
| id | doaj.art-19c55f9c70514139b6f03be535fd5818 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T02:06:01Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-19c55f9c70514139b6f03be535fd58182023-11-18T11:49:59ZengMDPI AGMolecules1420-30492023-06-012812476310.3390/molecules28124763The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass SpectrometryJunli Cao0Jindong Li1Pengcheng Ren2Yanli Qi3Shu Qin4Shanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, ChinaShanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, ChinaShanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, ChinaShanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, ChinaShanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, ChinaSpirotetramat is a potential tetronic acid pesticide for controlling various pests with piercing–sucking mouthparts. To clarify its dietary risk on cabbage, we established an ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method and then investigated the residual levels of spirotetramat and its four metabolites in cabbage collected from field experiments under good agricultural practices (GAPs). The average recoveries of spirotetramat and its metabolites in cabbage were 74~110%, while the relative standard deviation (RSD) was 1~6%, and the limit of quantitation (LOQ) was 0.01 mg kg<sup>−1</sup>. The terminal residue of spirotetramat was in the range of <0.05~0.33 mg kg<sup>−1</sup>, the chronic dietary risk (RQ<sub>c</sub>) was 17.56%, and the acute dietary risk (RQ<sub>a</sub>) was 0.025~0.049%, which means an acceptable dietary intake risk. This study provides data to guide on the use of spirotetramat and to establish the maximum residue limits (MRLs) of spirotetramat on cabbage.https://www.mdpi.com/1420-3049/28/12/4763spirotetramatcabbagedissipationdietary intake risk |
| spellingShingle | Junli Cao Jindong Li Pengcheng Ren Yanli Qi Shu Qin The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry Molecules spirotetramat cabbage dissipation dietary intake risk |
| title | The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_full | The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_fullStr | The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_full_unstemmed | The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_short | The Residue and Dietary Risk Assessment of Spirotetramat and Its Four Metabolites in Cabbage Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry |
| title_sort | residue and dietary risk assessment of spirotetramat and its four metabolites in cabbage using ultra high performance liquid chromatography tandem mass spectrometry |
| topic | spirotetramat cabbage dissipation dietary intake risk |
| url | https://www.mdpi.com/1420-3049/28/12/4763 |
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