Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022
Abstract Background It is usually difficult for the trough concentration of vancomycin to reach the recommended lower limit of 10 mg/L per the label dose in the paediatric population. Moreover, children with haematologic diseases who suffer from neutropenia are more likely to have lower exposure of...
Main Authors: | Fengjiao Wang, Mi Zhou, Wenjuan Wang, Zengyan Zhu, Yinghui Yan |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-10-01
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Series: | BMC Pediatrics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12887-023-04288-4 |
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