Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022

Abstract Background It is usually difficult for the trough concentration of vancomycin to reach the recommended lower limit of 10 mg/L per the label dose in the paediatric population. Moreover, children with haematologic diseases who suffer from neutropenia are more likely to have lower exposure of...

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Bibliographic Details
Main Authors: Fengjiao Wang, Mi Zhou, Wenjuan Wang, Zengyan Zhu, Yinghui Yan
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s12887-023-04288-4

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