Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review

Background: Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry. Case Presentation: We described 2 cases of PMT in the...

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Bibliographic Details
Main Authors: Ruifeng Wang, Jiayu Zhou, Yupei Yu, Junqi Deng, Ze Wu, Chunlin Ou, Yanhao Wu, Keda Yang, Junpu Wang
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Clinical Pathology
Online Access:https://doi.org/10.1177/2632010X221129588
Description
Summary:Background: Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry. Case Presentation: We described 2 cases of PMT in the right thigh with manifestations of hypophosphatemia. PET-CT examination showed that both patients had lesions with increased expression of somatostatin receptors in the right thigh. Bland cells and dirty calcified stroma were exhibited under the microscope. And immunohistochemical detection of FGF-23 was positive. Conclusions: PMT is a very uncommon tumor for which diagnosis and treatment are often delayed. Considering the importance of surgery for the treatment of this disease, a full understanding of its clinicopathological features will facilitate the diagnosis of this disease.
ISSN:2632-010X