Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review
Background: Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry. Case Presentation: We described 2 cases of PMT in the...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-10-01
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| Series: | Clinical Pathology |
| Online Access: | https://doi.org/10.1177/2632010X221129588 |
| _version_ | 1798029154123251712 |
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| author | Ruifeng Wang Jiayu Zhou Yupei Yu Junqi Deng Ze Wu Chunlin Ou Yanhao Wu Keda Yang Junpu Wang |
| author_facet | Ruifeng Wang Jiayu Zhou Yupei Yu Junqi Deng Ze Wu Chunlin Ou Yanhao Wu Keda Yang Junpu Wang |
| author_sort | Ruifeng Wang |
| collection | DOAJ |
| description | Background: Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry. Case Presentation: We described 2 cases of PMT in the right thigh with manifestations of hypophosphatemia. PET-CT examination showed that both patients had lesions with increased expression of somatostatin receptors in the right thigh. Bland cells and dirty calcified stroma were exhibited under the microscope. And immunohistochemical detection of FGF-23 was positive. Conclusions: PMT is a very uncommon tumor for which diagnosis and treatment are often delayed. Considering the importance of surgery for the treatment of this disease, a full understanding of its clinicopathological features will facilitate the diagnosis of this disease. |
| first_indexed | 2024-04-11T19:20:42Z |
| format | Article |
| id | doaj.art-19c8402befcc453aaf93bf3aeed548b2 |
| institution | Directory Open Access Journal |
| issn | 2632-010X |
| language | English |
| last_indexed | 2024-04-11T19:20:42Z |
| publishDate | 2022-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Pathology |
| spelling | doaj.art-19c8402befcc453aaf93bf3aeed548b22022-12-22T04:07:19ZengSAGE PublishingClinical Pathology2632-010X2022-10-011510.1177/2632010X221129588Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature reviewRuifeng Wang0Jiayu Zhou1Yupei Yu2Junqi Deng3Ze Wu4Chunlin Ou5Yanhao Wu6Keda Yang7Junpu Wang8Department of Pathology, School of Basic Medicine, Central South University, Changsha City, Hunan Province, ChinaDepartment of Pathology, School of Basic Medicine, Central South University, Changsha City, Hunan Province, ChinaDepartment of Pathology, School of Basic Medicine, Central South University, Changsha City, Hunan Province, ChinaDepartment of Pathology, School of Basic Medicine, Central South University, Changsha City, Hunan Province, ChinaDepartment of Pathology, Xiang-ya Hospital, Central South University, Changsha City, Hunan Province, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaDepartment of Pathology, School of Basic Medicine, Central South University, Changsha City, Hunan Province, ChinaUltrapathology (Biomedical electron microscopy) Center, Department of Pathology, Xiang-ya Hospital, Central South University, Changsha City, Hunan Province, ChinaBackground: Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry. Case Presentation: We described 2 cases of PMT in the right thigh with manifestations of hypophosphatemia. PET-CT examination showed that both patients had lesions with increased expression of somatostatin receptors in the right thigh. Bland cells and dirty calcified stroma were exhibited under the microscope. And immunohistochemical detection of FGF-23 was positive. Conclusions: PMT is a very uncommon tumor for which diagnosis and treatment are often delayed. Considering the importance of surgery for the treatment of this disease, a full understanding of its clinicopathological features will facilitate the diagnosis of this disease.https://doi.org/10.1177/2632010X221129588 |
| spellingShingle | Ruifeng Wang Jiayu Zhou Yupei Yu Junqi Deng Ze Wu Chunlin Ou Yanhao Wu Keda Yang Junpu Wang Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review Clinical Pathology |
| title | Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review |
| title_full | Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review |
| title_fullStr | Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review |
| title_full_unstemmed | Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review |
| title_short | Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review |
| title_sort | phosphaturic mesenchymal tumor in right thigh 2 cases report and literature review |
| url | https://doi.org/10.1177/2632010X221129588 |
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