Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities
Humans have utilised cannabis products in various forms throughout the recorded history. To date, more than 500 biologically active components have been identified in the plants of the Cannabis genus, amongst which more than 100 were classified as phytocannabinoids (exocannabinoids). The plant genus...
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| Format: | Article |
| Language: | English |
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AOSIS
2022-05-01
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| Series: | South African Family Practice |
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| Online Access: | https://safpj.co.za/index.php/safpj/article/view/5493 |
| _version_ | 1811256936875687936 |
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| author | Lehlohonolo Makhakhe |
| author_facet | Lehlohonolo Makhakhe |
| author_sort | Lehlohonolo Makhakhe |
| collection | DOAJ |
| description | Humans have utilised cannabis products in various forms throughout the recorded history. To date, more than 500 biologically active components have been identified in the plants of the Cannabis genus, amongst which more than 100 were classified as phytocannabinoids (exocannabinoids). The plant genus Cannabis is a member of the plant family Cannabaceae, and there are three primary cannabis species which vary in their biochemical constituents: Cannabis sativa, Cannabis indica and Cannabis ruderalis. There has been a growing level of interest in research on the topical usage of a cannabis-based extract as a safer and more effective alternative to the usage of topical corticosteroids in treating some dermatoses. Together with the discovery of the cannabinoid receptors on the skin, it has been further illustrated that topical cannabis has anti-inflammatory, anti-itching, analgesics, wound healing and anti-proliferative effects on the skin. |
| first_indexed | 2024-04-12T17:48:49Z |
| format | Article |
| id | doaj.art-19ce697e2f19428a9e570991e07b23db |
| institution | Directory Open Access Journal |
| issn | 2078-6190 2078-6204 |
| language | English |
| last_indexed | 2024-04-12T17:48:49Z |
| publishDate | 2022-05-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Family Practice |
| spelling | doaj.art-19ce697e2f19428a9e570991e07b23db2022-12-22T03:22:34ZengAOSISSouth African Family Practice2078-61902078-62042022-05-01641e1e410.4102/safp.v64i1.54934232Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunitiesLehlohonolo Makhakhe0Department of Dermatology, Faculty of Health Science, University of the Free State, Bloemfontein, South Africa; and, The South African Institute of Dermatology, BloemfonteinHumans have utilised cannabis products in various forms throughout the recorded history. To date, more than 500 biologically active components have been identified in the plants of the Cannabis genus, amongst which more than 100 were classified as phytocannabinoids (exocannabinoids). The plant genus Cannabis is a member of the plant family Cannabaceae, and there are three primary cannabis species which vary in their biochemical constituents: Cannabis sativa, Cannabis indica and Cannabis ruderalis. There has been a growing level of interest in research on the topical usage of a cannabis-based extract as a safer and more effective alternative to the usage of topical corticosteroids in treating some dermatoses. Together with the discovery of the cannabinoid receptors on the skin, it has been further illustrated that topical cannabis has anti-inflammatory, anti-itching, analgesics, wound healing and anti-proliferative effects on the skin.https://safpj.co.za/index.php/safpj/article/view/5493cannabisdermatologynew modality of treatmentanti-inflammatorytopical usage |
| spellingShingle | Lehlohonolo Makhakhe Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities South African Family Practice cannabis dermatology new modality of treatment anti-inflammatory topical usage |
| title | Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities |
| title_full | Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities |
| title_fullStr | Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities |
| title_full_unstemmed | Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities |
| title_short | Topical cannabidiol (CBD) in skin pathology – A comprehensive review and prospects for new therapeutic opportunities |
| title_sort | topical cannabidiol cbd in skin pathology a comprehensive review and prospects for new therapeutic opportunities |
| topic | cannabis dermatology new modality of treatment anti-inflammatory topical usage |
| url | https://safpj.co.za/index.php/safpj/article/view/5493 |
| work_keys_str_mv | AT lehlohonolomakhakhe topicalcannabidiolcbdinskinpathologyacomprehensivereviewandprospectsfornewtherapeuticopportunities |