Prior acute exercise restores postprandial fat oxidation in active cannabis users
Abstract Data suggest cannabis users have similar or lower levels of blood lipids compared to nonusers. However, the extent to which cannabis users experience postprandial lipemia is not known. Eleven cannabis users and 11 nonusers completed either rest or 1 h of exercise at their ventilatory thresh...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-03-01
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| Series: | Physiological Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.14814/phy2.15968 |
| _version_ | 1797262557901225984 |
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| author | Matthew M. Schubert Samantha Terauds Maren Plant Grace Handler Colin Atkins Casandra Mendez |
| author_facet | Matthew M. Schubert Samantha Terauds Maren Plant Grace Handler Colin Atkins Casandra Mendez |
| author_sort | Matthew M. Schubert |
| collection | DOAJ |
| description | Abstract Data suggest cannabis users have similar or lower levels of blood lipids compared to nonusers. However, the extent to which cannabis users experience postprandial lipemia is not known. Eleven cannabis users and 11 nonusers completed either rest or 1 h of exercise at their ventilatory threshold the evening before a meal tolerance test (MTT). Substrate oxidation, blood pressure, and capillary blood were obtained before and every 30–60 min post‐meal for 3 h. Linear mixed models were utilized to examine differences in variables between groups, conditions, across time, and their interactions. Exercise led to increased fat oxidation post‐MTT (p < 0.05), with cannabis users exhibiting higher AUC compared to the control trial (p < 0.05). Exercise also caused significantly lower levels of triglycerides (p < 0.05). Metabolic flexibility was improved in cannabis users in the exercise trial only (p < 0.05). No effect of group, trial, or interactions were detected for other variables of interest (all p > 0.05). This study indicated that prior exercise improves lipid metabolism in cannabis users and nonusers after a high‐fat meal test. Cannabis users appear sensitive to the effects of exercise. Future studies should incorporate additional meals and variables related to cardiovascular health and metabolism. |
| first_indexed | 2024-04-24T23:59:01Z |
| format | Article |
| id | doaj.art-19d0b8cb61124e7f9b8d1a94b70effd9 |
| institution | Directory Open Access Journal |
| issn | 2051-817X |
| language | English |
| last_indexed | 2024-04-24T23:59:01Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj.art-19d0b8cb61124e7f9b8d1a94b70effd92024-03-14T08:20:44ZengWileyPhysiological Reports2051-817X2024-03-01125n/an/a10.14814/phy2.15968Prior acute exercise restores postprandial fat oxidation in active cannabis usersMatthew M. Schubert0Samantha Terauds1Maren Plant2Grace Handler3Colin Atkins4Casandra Mendez5Metabolism and Applied Physiology Laboratory, Department of Kinesiology California State University San Marcos California USAMetabolism and Applied Physiology Laboratory, Department of Kinesiology California State University San Marcos California USASchool of Medicine George Washington University Washington DC USAMetabolism and Applied Physiology Laboratory, Department of Kinesiology California State University San Marcos California USAMetabolism and Applied Physiology Laboratory, Department of Kinesiology California State University San Marcos California USAMetabolism and Applied Physiology Laboratory, Department of Kinesiology California State University San Marcos California USAAbstract Data suggest cannabis users have similar or lower levels of blood lipids compared to nonusers. However, the extent to which cannabis users experience postprandial lipemia is not known. Eleven cannabis users and 11 nonusers completed either rest or 1 h of exercise at their ventilatory threshold the evening before a meal tolerance test (MTT). Substrate oxidation, blood pressure, and capillary blood were obtained before and every 30–60 min post‐meal for 3 h. Linear mixed models were utilized to examine differences in variables between groups, conditions, across time, and their interactions. Exercise led to increased fat oxidation post‐MTT (p < 0.05), with cannabis users exhibiting higher AUC compared to the control trial (p < 0.05). Exercise also caused significantly lower levels of triglycerides (p < 0.05). Metabolic flexibility was improved in cannabis users in the exercise trial only (p < 0.05). No effect of group, trial, or interactions were detected for other variables of interest (all p > 0.05). This study indicated that prior exercise improves lipid metabolism in cannabis users and nonusers after a high‐fat meal test. Cannabis users appear sensitive to the effects of exercise. Future studies should incorporate additional meals and variables related to cardiovascular health and metabolism.https://doi.org/10.14814/phy2.15968cannabisexerciselipidmetabolismsubstrates |
| spellingShingle | Matthew M. Schubert Samantha Terauds Maren Plant Grace Handler Colin Atkins Casandra Mendez Prior acute exercise restores postprandial fat oxidation in active cannabis users Physiological Reports cannabis exercise lipid metabolism substrates |
| title | Prior acute exercise restores postprandial fat oxidation in active cannabis users |
| title_full | Prior acute exercise restores postprandial fat oxidation in active cannabis users |
| title_fullStr | Prior acute exercise restores postprandial fat oxidation in active cannabis users |
| title_full_unstemmed | Prior acute exercise restores postprandial fat oxidation in active cannabis users |
| title_short | Prior acute exercise restores postprandial fat oxidation in active cannabis users |
| title_sort | prior acute exercise restores postprandial fat oxidation in active cannabis users |
| topic | cannabis exercise lipid metabolism substrates |
| url | https://doi.org/10.14814/phy2.15968 |
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