Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats
Penconazole (PEN) is a widely applied triazole fungicide. This study sought to define the efficacy of N-acetyl-l-cysteine (NAC) in mitigating PEN-triggered hepatorenal toxicity in rats.
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2023-09-01
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| Series: | Journal of Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/jvetres-2023-0039 |
| _version_ | 1797668688184213504 |
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| author | Morgan Ashraf M. Ogaly Hanan A. Kamel Shaimaa Rashad Maha M. Hassanen Eman I. Ibrahim Marwa A. Galal Mona K. Yassin Aya M. Dulmani Sharah A. Al Al-Zahrani Fatimah A.M. Hussien Ahmed M. |
| author_facet | Morgan Ashraf M. Ogaly Hanan A. Kamel Shaimaa Rashad Maha M. Hassanen Eman I. Ibrahim Marwa A. Galal Mona K. Yassin Aya M. Dulmani Sharah A. Al Al-Zahrani Fatimah A.M. Hussien Ahmed M. |
| author_sort | Morgan Ashraf M. |
| collection | DOAJ |
| description | Penconazole (PEN) is a widely applied triazole fungicide. This study sought to define the efficacy of N-acetyl-l-cysteine (NAC) in mitigating PEN-triggered hepatorenal toxicity in rats. |
| first_indexed | 2024-03-11T20:33:07Z |
| format | Article |
| id | doaj.art-19d17c1d86fc4623b1e63d54728a9526 |
| institution | Directory Open Access Journal |
| issn | 2450-8608 |
| language | English |
| last_indexed | 2024-03-11T20:33:07Z |
| publishDate | 2023-09-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Veterinary Research |
| spelling | doaj.art-19d17c1d86fc4623b1e63d54728a95262023-10-02T07:39:36ZengSciendoJournal of Veterinary Research2450-86082023-09-0167345946910.2478/jvetres-2023-0039Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult ratsMorgan Ashraf M.0Ogaly Hanan A.1Kamel Shaimaa2Rashad Maha M.3Hassanen Eman I.4Ibrahim Marwa A.5Galal Mona K.6Yassin Aya M.7Dulmani Sharah A. Al8Al-Zahrani Fatimah A.M.9Hussien Ahmed M.101Toxicology and Forensic Medicine Department, 12211Giza, Egypt2Chemistry Department, Faculty of Science, King Khalid University, Abha 62421, Abha High City, Saudi Arabia3Biochemistry and Molecular Biology Department, 12211Giza, Egypt3Biochemistry and Molecular Biology Department, 12211Giza, Egypt4Pathology Department, Faculty of Veterinary Medicine, Cairo University, 12211Giza, Egypt3Biochemistry and Molecular Biology Department, 12211Giza, Egypt3Biochemistry and Molecular Biology Department, 12211Giza, Egypt3Biochemistry and Molecular Biology Department, 12211Giza, Egypt2Chemistry Department, Faculty of Science, King Khalid University, Abha 62421, Abha High City, Saudi Arabia2Chemistry Department, Faculty of Science, King Khalid University, Abha 62421, Abha High City, Saudi Arabia1Toxicology and Forensic Medicine Department, 12211Giza, EgyptPenconazole (PEN) is a widely applied triazole fungicide. This study sought to define the efficacy of N-acetyl-l-cysteine (NAC) in mitigating PEN-triggered hepatorenal toxicity in rats.https://doi.org/10.2478/jvetres-2023-0039penconazolenrf2ho-1keap1nf-κb |
| spellingShingle | Morgan Ashraf M. Ogaly Hanan A. Kamel Shaimaa Rashad Maha M. Hassanen Eman I. Ibrahim Marwa A. Galal Mona K. Yassin Aya M. Dulmani Sharah A. Al Al-Zahrani Fatimah A.M. Hussien Ahmed M. Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats Journal of Veterinary Research penconazole nrf2 ho-1 keap1 nf-κb |
| title | Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats |
| title_full | Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats |
| title_fullStr | Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats |
| title_full_unstemmed | Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats |
| title_short | Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats |
| title_sort | protective effects of n acetyl l cysteine against penconazole triggered hepatorenal toxicity in adult rats |
| topic | penconazole nrf2 ho-1 keap1 nf-κb |
| url | https://doi.org/10.2478/jvetres-2023-0039 |
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