Calcium channel blockers, more than diuretics, enhance vascular protective effects of angiotensin receptor blockers in salt-loaded hypertensive rats.

Calcium channel blockers, more than diuretics, enhance vascular protective effects of angiotensin receptor blockers in salt-loaded hypertensive rats.

The combination therapy of an angiotensin receptor blocker (ARB) with a calcium channel blocker (CCB) or with a diuretic is favorably recommended for the treatment of hypertension. However, the difference between these two combination therapies is unclear. The present work was undertaken to examine...

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Bibliographic Details
Main Authors: Eiichiro Yamamoto, Keiichiro Kataoka, Yi-Fei Dong, Nobutaka Koibuchi, Kensuke Toyama, Daisuke Sueta, Tetsuji Katayama, Osamu Yasuda, Hisao Ogawa, Shokei Kim-Mitsuyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3375277?pdf=render

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