ANKLE1 as New Hotspot Mutation for Breast Cancer in Indian Population and Has a Role in DNA Damage and Repair in Mammalian Cells

ANKLE1 as New Hotspot Mutation for Breast Cancer in Indian Population and Has a Role in DNA Damage and Repair in Mammalian Cells

Breast cancer has replaced cervical cancer as being the most common and having the highest mortality among women in India. ANKLE gene is conserved among organisms during evolutionary succession and is a member of LEM family proteins in lower metazoans and is involved in critical functions in the nuc...

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Bibliographic Details
Main Authors: Divya Bakshi, Archana Katoch, Souneek Chakraborty, Ruchi Shah, Bhanu Sharma, Amrita Bhat, Sonali Verma, Gh. Rasool Bhat, Ashna Nagpal, Samantha Vaishnavi, Anindya Goswami, Rakesh Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
ANKLE-1
γH2AX
cancer
breast cancer
MCF-7 cell line
DNA damage
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.609758/full

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