A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen Matrix
Emilio Rintaro Suzuki Junior,1 Heloisa Andrade Maestrini,2 Aline Domingos Pinto Ruppert,3 Regina Cele Silveira Seixas,3 Ana Flávia Belfort,4 Herika Danielle de Miranda Santos,2 Alberto Basile Neto,5 Marcos Balbino,6 Marcelo Jordão Lopes da Silva7 1Department of Ophthalmology, Pontifícia Universidade...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-01-01
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| Series: | Clinical Ophthalmology |
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| Online Access: | https://www.dovepress.com/a-retrospective-comparison-of-ahmed-glaucoma-valve-implants-with-or-wi-peer-reviewed-fulltext-article-OPTH |
| _version_ | 1797955532132188160 |
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| author | Suzuki Junior ER Maestrini HA Ruppert ADP Seixas RCS Belfort AF de Miranda Santos HD Basile Neto A Balbino M Lopes da Silva MJ |
| author_facet | Suzuki Junior ER Maestrini HA Ruppert ADP Seixas RCS Belfort AF de Miranda Santos HD Basile Neto A Balbino M Lopes da Silva MJ |
| author_sort | Suzuki Junior ER |
| collection | DOAJ |
| description | Emilio Rintaro Suzuki Junior,1 Heloisa Andrade Maestrini,2 Aline Domingos Pinto Ruppert,3 Regina Cele Silveira Seixas,3 Ana Flávia Belfort,4 Herika Danielle de Miranda Santos,2 Alberto Basile Neto,5 Marcos Balbino,6 Marcelo Jordão Lopes da Silva7 1Department of Ophthalmology, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, MG, Brazil; 2Department of Ophthalmology, Hospital Oculare, Belo Horizonte, MG, Brazil; 3Department of Ophthalmology, Grupo OPTY – HCLOE – Oftalmologia Especializada, São Paulo, SP, Brazil; 4Department of Ophthalmology, Clínica de Olhos da Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil; 5Department of Ophthalmology, Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, Brazil; 6Department of Emergency Medicine, Centro Universitário São Camilo, São Paulo, SP, Brazil; 7Department of Ophthalmology, Oftalmocenter Ribeirão Preto, Ribeirão Preto, SP, BrazilCorrespondence: Marcos Balbino, Department of Emergency Medicine, Centro Universitário São Camilo, Cipriano Barata, 1869 – ap. 93. Ipiranga, São Paulo, 04205001, Brazil, Tel +5511-983462354, Email marcosbalbino@mac.comPurpose: To study the effects of Ologen collagen matrix on the outcomes of the Ahmed glaucoma valve implant.Study Design: Retrospective case-control multicenter study, conducted at four centers, comparing the 6-month outcomes of Ahmed valve implants with or without Ologen.Participants: The study included 125 eyes in a 4:1 pairing (25 patients with Ologen matched to 100 patients without Ologen).Intervention: Ologen was placed over the Ahmed plate in the study group. Success was defined as an intraocular pressure (IOP) ≤ 21 mmHg either with no medication (complete success) or regardless of medications (qualified success). Other outcomes included IOP variation, eye drop use, and surgical complications.Results: Overall, the IOP decreased from 30.72 ± 9.08 to 16.14 ± 4.79 mmHg (p=0.0001). Of the 125 eyes, 26 achieved complete success and 94 achieved qualified success. There was no difference in complete success between the groups (p=0.12); however, there was a difference in qualified success (p=0.01), with better results in the no-Ologen group (80% vs 56%). There were no differences in the decrease in medications (p=0.06), as well as the incidence of complications (p=0.69). Although the need for postoperative surgical reintervention was higher in the no-Ologen group (13% vs 4%), the difference was not significant (p=0.2).Conclusion: The reductions in IOP and number of medications were similar in both groups after 6 months, with similar complication rates. The qualified success rate was lower in the Ologen group, but further studies are needed to clarify the role of Ologen in Ahmed valve implants.Keywords: glaucoma, tube shunts, glaucoma incisional surgery, glaucoma anti-fibrotic agents, postoperative glaucoma hypotony |
| first_indexed | 2024-04-10T23:35:47Z |
| format | Article |
| id | doaj.art-19d8fc5d5d5d46a587ecf82bd631b11a |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-04-10T23:35:47Z |
| publishDate | 2023-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-19d8fc5d5d5d46a587ecf82bd631b11a2023-01-11T19:18:14ZengDove Medical PressClinical Ophthalmology1177-54832023-01-01Volume 17152380760A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen MatrixSuzuki Junior ERMaestrini HARuppert ADPSeixas RCSBelfort AFde Miranda Santos HDBasile Neto ABalbino MLopes da Silva MJEmilio Rintaro Suzuki Junior,1 Heloisa Andrade Maestrini,2 Aline Domingos Pinto Ruppert,3 Regina Cele Silveira Seixas,3 Ana Flávia Belfort,4 Herika Danielle de Miranda Santos,2 Alberto Basile Neto,5 Marcos Balbino,6 Marcelo Jordão Lopes da Silva7 1Department of Ophthalmology, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, MG, Brazil; 2Department of Ophthalmology, Hospital Oculare, Belo Horizonte, MG, Brazil; 3Department of Ophthalmology, Grupo OPTY – HCLOE – Oftalmologia Especializada, São Paulo, SP, Brazil; 4Department of Ophthalmology, Clínica de Olhos da Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil; 5Department of Ophthalmology, Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, Brazil; 6Department of Emergency Medicine, Centro Universitário São Camilo, São Paulo, SP, Brazil; 7Department of Ophthalmology, Oftalmocenter Ribeirão Preto, Ribeirão Preto, SP, BrazilCorrespondence: Marcos Balbino, Department of Emergency Medicine, Centro Universitário São Camilo, Cipriano Barata, 1869 – ap. 93. Ipiranga, São Paulo, 04205001, Brazil, Tel +5511-983462354, Email marcosbalbino@mac.comPurpose: To study the effects of Ologen collagen matrix on the outcomes of the Ahmed glaucoma valve implant.Study Design: Retrospective case-control multicenter study, conducted at four centers, comparing the 6-month outcomes of Ahmed valve implants with or without Ologen.Participants: The study included 125 eyes in a 4:1 pairing (25 patients with Ologen matched to 100 patients without Ologen).Intervention: Ologen was placed over the Ahmed plate in the study group. Success was defined as an intraocular pressure (IOP) ≤ 21 mmHg either with no medication (complete success) or regardless of medications (qualified success). Other outcomes included IOP variation, eye drop use, and surgical complications.Results: Overall, the IOP decreased from 30.72 ± 9.08 to 16.14 ± 4.79 mmHg (p=0.0001). Of the 125 eyes, 26 achieved complete success and 94 achieved qualified success. There was no difference in complete success between the groups (p=0.12); however, there was a difference in qualified success (p=0.01), with better results in the no-Ologen group (80% vs 56%). There were no differences in the decrease in medications (p=0.06), as well as the incidence of complications (p=0.69). Although the need for postoperative surgical reintervention was higher in the no-Ologen group (13% vs 4%), the difference was not significant (p=0.2).Conclusion: The reductions in IOP and number of medications were similar in both groups after 6 months, with similar complication rates. The qualified success rate was lower in the Ologen group, but further studies are needed to clarify the role of Ologen in Ahmed valve implants.Keywords: glaucoma, tube shunts, glaucoma incisional surgery, glaucoma anti-fibrotic agents, postoperative glaucoma hypotonyhttps://www.dovepress.com/a-retrospective-comparison-of-ahmed-glaucoma-valve-implants-with-or-wi-peer-reviewed-fulltext-article-OPTHglaucomatube shuntsglaucoma incisional surgeryglaucoma anti-fibrotic agentspostoperative glaucoma hypotony. |
| spellingShingle | Suzuki Junior ER Maestrini HA Ruppert ADP Seixas RCS Belfort AF de Miranda Santos HD Basile Neto A Balbino M Lopes da Silva MJ A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen Matrix Clinical Ophthalmology glaucoma tube shunts glaucoma incisional surgery glaucoma anti-fibrotic agents postoperative glaucoma hypotony. |
| title | A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen Matrix |
| title_full | A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen Matrix |
| title_fullStr | A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen Matrix |
| title_full_unstemmed | A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen Matrix |
| title_short | A Retrospective Comparison of Ahmed Glaucoma Valve Implants with or without Ologen Collagen Matrix |
| title_sort | retrospective comparison of ahmed glaucoma valve implants with or without ologen collagen matrix |
| topic | glaucoma tube shunts glaucoma incisional surgery glaucoma anti-fibrotic agents postoperative glaucoma hypotony. |
| url | https://www.dovepress.com/a-retrospective-comparison-of-ahmed-glaucoma-valve-implants-with-or-wi-peer-reviewed-fulltext-article-OPTH |
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