Contextual Fear Memory Maintenance Changes Expression of pMAPK, BDNF and IBA-1 in the Pre-limbic Cortex in a Layer-Specific Manner

Contextual Fear Memory Maintenance Changes Expression of pMAPK, BDNF and IBA-1 in the Pre-limbic Cortex in a Layer-Specific Manner

Post-traumatic stress disorder (PTSD) is a debilitating and chronic fear-based disorder. Pavlovian fear conditioning protocols have long been utilised to manipulate and study these fear-based disorders. Contextual fear conditioning (CFC) is a particular Pavlovian conditioning procedure that pairs fe...

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Bibliographic Details
Main Authors: Nicholas Chaaya, Joshua Wang, Angela Jacques, Kate Beecher, Michael Chaaya, Andrew Raymond Battle, Luke R. Johnson, Fatemeh Chehrehasa, Arnauld Belmer, Selena E. Bartlett
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neural Circuits
Subjects:
fear
learning and memory
plasticity
prelimbic cortex
brain derived neurotrophic factor (BDNF)
Online Access:https://www.frontiersin.org/articles/10.3389/fncir.2021.660199/full

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