Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticles
In this study, metal oxide (MO) nanoparticles were synthesized using a microwave and chemical methods and characterized using spectroscopic and microscopic techniques such as scanning electron microscopy (SEM), UV–vis spectroscopy, FTIR spectroscopy and Zeta potential analysis. The sensitivity (grow...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IOP Publishing
2020-01-01
|
| Series: | Materials Research Express |
| Subjects: | |
| Online Access: | https://doi.org/10.1088/2053-1591/ab6645 |
| _version_ | 1797747058150473728 |
|---|---|
| author | Olaoluwa Ruth Obisesan Abolanle Saheed Adekunle John Adekunle O Oyekunle Aderemi Okunola Ogunfowokan Olarinde Olaniran Sabu Thomas Thabo T I Nkambule Bhekie B Mamba |
| author_facet | Olaoluwa Ruth Obisesan Abolanle Saheed Adekunle John Adekunle O Oyekunle Aderemi Okunola Ogunfowokan Olarinde Olaniran Sabu Thomas Thabo T I Nkambule Bhekie B Mamba |
| author_sort | Olaoluwa Ruth Obisesan |
| collection | DOAJ |
| description | In this study, metal oxide (MO) nanoparticles were synthesized using a microwave and chemical methods and characterized using spectroscopic and microscopic techniques such as scanning electron microscopy (SEM), UV–vis spectroscopy, FTIR spectroscopy and Zeta potential analysis. The sensitivity (growth of inhibition) and catalytic degradation study of the MO nanoparticles with malaria biomarker ( β -Hematin) and cultured Salmonella typhi was established. Both the chemical and microwave synthesized metal oxide nanoparticles exhibited effective potential to degrade the malaria biomarker at different degree and to its less active by-product. However, in most cases, microwave synthesized nanoparticles performed better than their chemically synthesized counterparts. The synthesized nanoparticles show high antibacterial activity towards clinical pathogens and S. typhi and therefore can be used for sensor development for monitoring these microorganisms in biological fluids such as blood, and urine samples. |
| first_indexed | 2024-03-12T15:45:43Z |
| format | Article |
| id | doaj.art-19db97815a0a4bdd837c98974f521915 |
| institution | Directory Open Access Journal |
| issn | 2053-1591 |
| language | English |
| last_indexed | 2024-03-12T15:45:43Z |
| publishDate | 2020-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Research Express |
| spelling | doaj.art-19db97815a0a4bdd837c98974f5219152023-08-09T15:26:24ZengIOP PublishingMaterials Research Express2053-15912020-01-017101504410.1088/2053-1591/ab6645Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticlesOlaoluwa Ruth Obisesan0https://orcid.org/0000-0002-7265-9010Abolanle Saheed Adekunle1https://orcid.org/0000-0002-2174-7600John Adekunle O Oyekunle2Aderemi Okunola Ogunfowokan3Olarinde Olaniran4Sabu Thomas5Thabo T I Nkambule6Bhekie B Mamba7Department of Chemistry, Obafemi Awolowo University , Ile-Ife, NigeriaDepartment of Chemistry, Obafemi Awolowo University , Ile-Ife, NigeriaDepartment of Chemistry, Obafemi Awolowo University , Ile-Ife, NigeriaDepartment of Chemistry, Obafemi Awolowo University , Ile-Ife, NigeriaDepartment of Medical Microbiology and Parasitology, Obafemi Awolowo University , Ile-Ife, NigeriaInternational and Inter University center for Nanoscience and Nanotechnology, Mahatma Gandhi University , Kottayam, IndiaNanotechnology and Water Sustainability Research Unit, College of Science, Engineering and Technology, Unveristy of South Africa , Johannesburg, South AfricaNanotechnology and Water Sustainability Research Unit, College of Science, Engineering and Technology, Unveristy of South Africa , Johannesburg, South AfricaIn this study, metal oxide (MO) nanoparticles were synthesized using a microwave and chemical methods and characterized using spectroscopic and microscopic techniques such as scanning electron microscopy (SEM), UV–vis spectroscopy, FTIR spectroscopy and Zeta potential analysis. The sensitivity (growth of inhibition) and catalytic degradation study of the MO nanoparticles with malaria biomarker ( β -Hematin) and cultured Salmonella typhi was established. Both the chemical and microwave synthesized metal oxide nanoparticles exhibited effective potential to degrade the malaria biomarker at different degree and to its less active by-product. However, in most cases, microwave synthesized nanoparticles performed better than their chemically synthesized counterparts. The synthesized nanoparticles show high antibacterial activity towards clinical pathogens and S. typhi and therefore can be used for sensor development for monitoring these microorganisms in biological fluids such as blood, and urine samples.https://doi.org/10.1088/2053-1591/ab6645β-hematinsalmonella typhimetal oxide nanoparticlescatalytic degradationantibacterial activityclinical pathogens |
| spellingShingle | Olaoluwa Ruth Obisesan Abolanle Saheed Adekunle John Adekunle O Oyekunle Aderemi Okunola Ogunfowokan Olarinde Olaniran Sabu Thomas Thabo T I Nkambule Bhekie B Mamba Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticles Materials Research Express β-hematin salmonella typhi metal oxide nanoparticles catalytic degradation antibacterial activity clinical pathogens |
| title | Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticles |
| title_full | Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticles |
| title_fullStr | Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticles |
| title_full_unstemmed | Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticles |
| title_short | Catalytic degradation of β–hematin (malaria biomaker) using some selected metal oxide nanoparticles |
| title_sort | catalytic degradation of β hematin malaria biomaker using some selected metal oxide nanoparticles |
| topic | β-hematin salmonella typhi metal oxide nanoparticles catalytic degradation antibacterial activity clinical pathogens |
| url | https://doi.org/10.1088/2053-1591/ab6645 |
| work_keys_str_mv | AT olaoluwaruthobisesan catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles AT abolanlesaheedadekunle catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles AT johnadekunleooyekunle catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles AT aderemiokunolaogunfowokan catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles AT olarindeolaniran catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles AT sabuthomas catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles AT thabotinkambule catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles AT bhekiebmamba catalyticdegradationofbhematinmalariabiomakerusingsomeselectedmetaloxidenanoparticles |