Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes

Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes

<p>Abstract</p> <p>Background</p> <p>Two recombinant, live attenuated human parainfluenza virus type 1 (rHPIV1) mutant viruses have been developed, using a reverse genetics system, for evaluation as potential intranasal vaccine candidates. These rHPIV1 vaccine candidate...

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Bibliographic Details
Main Authors: Skiadopoulos Mario H, Collins Peter L, Surman Sonja R, Castaño Adam, Bartlett Emmalene J, Murphy Brian R
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/4/1/67

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