Challenges in estimating the severity of kidney dysfunction in critically ill children
Acute kidney injury (AKI) is a common problem in critical care settings and conferred an increased risk of morbidities and mortality. The pendulum has shifted to the increasing number of children with comorbidities exposed to potential kidney damage. AKI is a complex clinical syndrome due to heterog...
| Main Authors: | , , |
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| Format: | Article |
| Sprog: | English |
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Wolters Kluwer Medknow Publications
2024-07-01
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| Serier: | Journal of Pediatric Critical Care |
| Fag: | |
| Online adgang: | https://journals.lww.com/10.4103/jpcc.jpcc_44_24 |
| _version_ | 1827157058295693312 |
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| author | Ramachandran Rameshkumar Muthu Chidambaram Rohit Bhowmick |
| author_facet | Ramachandran Rameshkumar Muthu Chidambaram Rohit Bhowmick |
| author_sort | Ramachandran Rameshkumar |
| collection | DOAJ |
| description | Acute kidney injury (AKI) is a common problem in critical care settings and conferred an increased risk of morbidities and mortality. The pendulum has shifted to the increasing number of children with comorbidities exposed to potential kidney damage. AKI is a complex clinical syndrome due to heterogeneous etiology. There has been an evolution in the definition and staging of AKI over the past two decades. However, estimating glomerular filtration rate in rapidly changing kidney function remains challenging. Although biomarkers are promising in AKI identification, timing is crucial in deciding which biomarker to measure. The outcome of AKI is not always recovery, but it is an interconnected syndrome with acute and chronic kidney disease. |
| first_indexed | 2025-03-20T23:19:18Z |
| format | Article |
| id | doaj.art-19e1f4d29abf42c394eeb51a4ef84ab3 |
| institution | Directory Open Access Journal |
| issn | 2349-6592 2455-7099 |
| language | English |
| last_indexed | 2025-03-20T23:19:18Z |
| publishDate | 2024-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pediatric Critical Care |
| spelling | doaj.art-19e1f4d29abf42c394eeb51a4ef84ab32024-08-04T09:55:39ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992024-07-0111415416110.4103/jpcc.jpcc_44_24Challenges in estimating the severity of kidney dysfunction in critically ill childrenRamachandran RameshkumarMuthu ChidambaramRohit BhowmickAcute kidney injury (AKI) is a common problem in critical care settings and conferred an increased risk of morbidities and mortality. The pendulum has shifted to the increasing number of children with comorbidities exposed to potential kidney damage. AKI is a complex clinical syndrome due to heterogeneous etiology. There has been an evolution in the definition and staging of AKI over the past two decades. However, estimating glomerular filtration rate in rapidly changing kidney function remains challenging. Although biomarkers are promising in AKI identification, timing is crucial in deciding which biomarker to measure. The outcome of AKI is not always recovery, but it is an interconnected syndrome with acute and chronic kidney disease.https://journals.lww.com/10.4103/jpcc.jpcc_44_24acute kidney injurybiomarkerschildrendefinitionspediatric intensive care unit |
| spellingShingle | Ramachandran Rameshkumar Muthu Chidambaram Rohit Bhowmick Challenges in estimating the severity of kidney dysfunction in critically ill children Journal of Pediatric Critical Care acute kidney injury biomarkers children definitions pediatric intensive care unit |
| title | Challenges in estimating the severity of kidney dysfunction in critically ill children |
| title_full | Challenges in estimating the severity of kidney dysfunction in critically ill children |
| title_fullStr | Challenges in estimating the severity of kidney dysfunction in critically ill children |
| title_full_unstemmed | Challenges in estimating the severity of kidney dysfunction in critically ill children |
| title_short | Challenges in estimating the severity of kidney dysfunction in critically ill children |
| title_sort | challenges in estimating the severity of kidney dysfunction in critically ill children |
| topic | acute kidney injury biomarkers children definitions pediatric intensive care unit |
| url | https://journals.lww.com/10.4103/jpcc.jpcc_44_24 |
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