A case of localized nasopharyngeal amyloidosis

Amyloidosis rarely occurs in the head and neck region and is extremely rare in the nasopharynx (3%). We encountered a case of nasopharyngeal amyloidosis discovered because of exudative otitis media. The patient presented to a local otolaryngology department with complaints of hearing loss, right exu...

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Main Authors: Ryota Tomioka, Teruhisa Yano, Kiyoaki Tsukahara
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Otolaryngology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468548821000394
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author Ryota Tomioka
Teruhisa Yano
Kiyoaki Tsukahara
author_facet Ryota Tomioka
Teruhisa Yano
Kiyoaki Tsukahara
author_sort Ryota Tomioka
collection DOAJ
description Amyloidosis rarely occurs in the head and neck region and is extremely rare in the nasopharynx (3%). We encountered a case of nasopharyngeal amyloidosis discovered because of exudative otitis media. The patient presented to a local otolaryngology department with complaints of hearing loss, right exudative otitis media, and a nasopharyngeal mass. She was referred to our department for consultation. A diagnosis of AA type amyloidosis was made based on a biopsy of the mass. In a detailed systemic examination in internal medicine, there were no findings suggestive of systemic amyloidosis or the presence of a primary disease, leading to a diagnosis of localized nasopharyngeal amyloidosis. Surgical resection was difficult. However, in outpatient follow-up, no signs of a change to the systemic type were observed. If amyloid deposition is discovered in a particular organ, the prognosis is good if it is localized. It is however imperative to check whether it has a systemic nature through a detailed systemic examination. In addition, as the AA type may be secondary to rheumatoid arthritis or collagen disease, it is important to determine if there is a primary disease through a detailed examination. Since the transformation of localized amyloidosis to the systemic type has been reported, stringent follow-up is important.
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spelling doaj.art-19e20d98715f44a7b899bfc07f0631f62022-12-21T21:31:26ZengElsevierOtolaryngology Case Reports2468-54882021-09-0120100299A case of localized nasopharyngeal amyloidosisRyota Tomioka0Teruhisa Yano1Kiyoaki Tsukahara2Corresponding author.; Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Nishi-Shinjuku 6-7-1, Shinjuku-ku, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Nishi-Shinjuku 6-7-1, Shinjuku-ku, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Nishi-Shinjuku 6-7-1, Shinjuku-ku, Tokyo, JapanAmyloidosis rarely occurs in the head and neck region and is extremely rare in the nasopharynx (3%). We encountered a case of nasopharyngeal amyloidosis discovered because of exudative otitis media. The patient presented to a local otolaryngology department with complaints of hearing loss, right exudative otitis media, and a nasopharyngeal mass. She was referred to our department for consultation. A diagnosis of AA type amyloidosis was made based on a biopsy of the mass. In a detailed systemic examination in internal medicine, there were no findings suggestive of systemic amyloidosis or the presence of a primary disease, leading to a diagnosis of localized nasopharyngeal amyloidosis. Surgical resection was difficult. However, in outpatient follow-up, no signs of a change to the systemic type were observed. If amyloid deposition is discovered in a particular organ, the prognosis is good if it is localized. It is however imperative to check whether it has a systemic nature through a detailed systemic examination. In addition, as the AA type may be secondary to rheumatoid arthritis or collagen disease, it is important to determine if there is a primary disease through a detailed examination. Since the transformation of localized amyloidosis to the systemic type has been reported, stringent follow-up is important.http://www.sciencedirect.com/science/article/pii/S2468548821000394Localized amyloidosisNasopharynxAA type amyloidosis
spellingShingle Ryota Tomioka
Teruhisa Yano
Kiyoaki Tsukahara
A case of localized nasopharyngeal amyloidosis
Otolaryngology Case Reports
Localized amyloidosis
Nasopharynx
AA type amyloidosis
title A case of localized nasopharyngeal amyloidosis
title_full A case of localized nasopharyngeal amyloidosis
title_fullStr A case of localized nasopharyngeal amyloidosis
title_full_unstemmed A case of localized nasopharyngeal amyloidosis
title_short A case of localized nasopharyngeal amyloidosis
title_sort case of localized nasopharyngeal amyloidosis
topic Localized amyloidosis
Nasopharynx
AA type amyloidosis
url http://www.sciencedirect.com/science/article/pii/S2468548821000394
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