A case of localized nasopharyngeal amyloidosis
Amyloidosis rarely occurs in the head and neck region and is extremely rare in the nasopharynx (3%). We encountered a case of nasopharyngeal amyloidosis discovered because of exudative otitis media. The patient presented to a local otolaryngology department with complaints of hearing loss, right exu...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
|
Series: | Otolaryngology Case Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2468548821000394 |
_version_ | 1818725699348856832 |
---|---|
author | Ryota Tomioka Teruhisa Yano Kiyoaki Tsukahara |
author_facet | Ryota Tomioka Teruhisa Yano Kiyoaki Tsukahara |
author_sort | Ryota Tomioka |
collection | DOAJ |
description | Amyloidosis rarely occurs in the head and neck region and is extremely rare in the nasopharynx (3%). We encountered a case of nasopharyngeal amyloidosis discovered because of exudative otitis media. The patient presented to a local otolaryngology department with complaints of hearing loss, right exudative otitis media, and a nasopharyngeal mass. She was referred to our department for consultation. A diagnosis of AA type amyloidosis was made based on a biopsy of the mass. In a detailed systemic examination in internal medicine, there were no findings suggestive of systemic amyloidosis or the presence of a primary disease, leading to a diagnosis of localized nasopharyngeal amyloidosis. Surgical resection was difficult. However, in outpatient follow-up, no signs of a change to the systemic type were observed. If amyloid deposition is discovered in a particular organ, the prognosis is good if it is localized. It is however imperative to check whether it has a systemic nature through a detailed systemic examination. In addition, as the AA type may be secondary to rheumatoid arthritis or collagen disease, it is important to determine if there is a primary disease through a detailed examination. Since the transformation of localized amyloidosis to the systemic type has been reported, stringent follow-up is important. |
first_indexed | 2024-12-17T21:46:28Z |
format | Article |
id | doaj.art-19e20d98715f44a7b899bfc07f0631f6 |
institution | Directory Open Access Journal |
issn | 2468-5488 |
language | English |
last_indexed | 2024-12-17T21:46:28Z |
publishDate | 2021-09-01 |
publisher | Elsevier |
record_format | Article |
series | Otolaryngology Case Reports |
spelling | doaj.art-19e20d98715f44a7b899bfc07f0631f62022-12-21T21:31:26ZengElsevierOtolaryngology Case Reports2468-54882021-09-0120100299A case of localized nasopharyngeal amyloidosisRyota Tomioka0Teruhisa Yano1Kiyoaki Tsukahara2Corresponding author.; Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Nishi-Shinjuku 6-7-1, Shinjuku-ku, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Nishi-Shinjuku 6-7-1, Shinjuku-ku, Tokyo, JapanDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Nishi-Shinjuku 6-7-1, Shinjuku-ku, Tokyo, JapanAmyloidosis rarely occurs in the head and neck region and is extremely rare in the nasopharynx (3%). We encountered a case of nasopharyngeal amyloidosis discovered because of exudative otitis media. The patient presented to a local otolaryngology department with complaints of hearing loss, right exudative otitis media, and a nasopharyngeal mass. She was referred to our department for consultation. A diagnosis of AA type amyloidosis was made based on a biopsy of the mass. In a detailed systemic examination in internal medicine, there were no findings suggestive of systemic amyloidosis or the presence of a primary disease, leading to a diagnosis of localized nasopharyngeal amyloidosis. Surgical resection was difficult. However, in outpatient follow-up, no signs of a change to the systemic type were observed. If amyloid deposition is discovered in a particular organ, the prognosis is good if it is localized. It is however imperative to check whether it has a systemic nature through a detailed systemic examination. In addition, as the AA type may be secondary to rheumatoid arthritis or collagen disease, it is important to determine if there is a primary disease through a detailed examination. Since the transformation of localized amyloidosis to the systemic type has been reported, stringent follow-up is important.http://www.sciencedirect.com/science/article/pii/S2468548821000394Localized amyloidosisNasopharynxAA type amyloidosis |
spellingShingle | Ryota Tomioka Teruhisa Yano Kiyoaki Tsukahara A case of localized nasopharyngeal amyloidosis Otolaryngology Case Reports Localized amyloidosis Nasopharynx AA type amyloidosis |
title | A case of localized nasopharyngeal amyloidosis |
title_full | A case of localized nasopharyngeal amyloidosis |
title_fullStr | A case of localized nasopharyngeal amyloidosis |
title_full_unstemmed | A case of localized nasopharyngeal amyloidosis |
title_short | A case of localized nasopharyngeal amyloidosis |
title_sort | case of localized nasopharyngeal amyloidosis |
topic | Localized amyloidosis Nasopharynx AA type amyloidosis |
url | http://www.sciencedirect.com/science/article/pii/S2468548821000394 |
work_keys_str_mv | AT ryotatomioka acaseoflocalizednasopharyngealamyloidosis AT teruhisayano acaseoflocalizednasopharyngealamyloidosis AT kiyoakitsukahara acaseoflocalizednasopharyngealamyloidosis AT ryotatomioka caseoflocalizednasopharyngealamyloidosis AT teruhisayano caseoflocalizednasopharyngealamyloidosis AT kiyoakitsukahara caseoflocalizednasopharyngealamyloidosis |