In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentations
We report three elderly patients with follicular lymphoma in situ (FLIS) each highlighting a unique pattern of disease presentation and progression. The first patient had incidentally detected FLIS with peripheral blood spill and yet had an 11-year uneventful follow up. The second patient with an ov...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=2;spage=218;epage=221;aulast=Sakhadeo |
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| author | Uma Sakhadeo Ashwini Mane Tanuja Shet |
| author_facet | Uma Sakhadeo Ashwini Mane Tanuja Shet |
| author_sort | Uma Sakhadeo |
| collection | DOAJ |
| description | We report three elderly patients with follicular lymphoma in situ (FLIS) each highlighting a unique pattern of disease presentation and progression. The first patient had incidentally detected FLIS with peripheral blood spill and yet had an 11-year uneventful follow up. The second patient with an overt follicular lymphoma (FL) developed high-grade transformation in jejunum with FLIS extensively involving the Payers patches. The third patient had a FLIS but that qualified as higher grade and was treated in spite of lack of overt FL mainly because of higher grade and patient subsequently did develop overt FL. The first case of typical FLIS confirms that peripheral blood spill does not connote poor prognosis in FLIS, the second case illustrates that FLIS may colonize mucosa-associated lymphoid tissue as part of homing in process of a disseminated FL and the third case validates the aggressive nature of high-grade FLIS. |
| first_indexed | 2024-04-13T21:02:27Z |
| format | Article |
| id | doaj.art-19e827d08f7749728d0fd745bc79825c |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-04-13T21:02:27Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-19e827d08f7749728d0fd745bc79825c2022-12-22T02:30:06ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292012-01-0155221822110.4103/0377-4929.97878In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentationsUma SakhadeoAshwini ManeTanuja ShetWe report three elderly patients with follicular lymphoma in situ (FLIS) each highlighting a unique pattern of disease presentation and progression. The first patient had incidentally detected FLIS with peripheral blood spill and yet had an 11-year uneventful follow up. The second patient with an overt follicular lymphoma (FL) developed high-grade transformation in jejunum with FLIS extensively involving the Payers patches. The third patient had a FLIS but that qualified as higher grade and was treated in spite of lack of overt FL mainly because of higher grade and patient subsequently did develop overt FL. The first case of typical FLIS confirms that peripheral blood spill does not connote poor prognosis in FLIS, the second case illustrates that FLIS may colonize mucosa-associated lymphoid tissue as part of homing in process of a disseminated FL and the third case validates the aggressive nature of high-grade FLIS.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=2;spage=218;epage=221;aulast=SakhadeoFollicular lymphomafollicular lymphoma in situnon-Hodgkin′s lymphoma |
| spellingShingle | Uma Sakhadeo Ashwini Mane Tanuja Shet In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentations Indian Journal of Pathology and Microbiology Follicular lymphoma follicular lymphoma in situ non-Hodgkin′s lymphoma |
| title | In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentations |
| title_full | In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentations |
| title_fullStr | In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentations |
| title_full_unstemmed | In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentations |
| title_short | In situ follicular neoplasia/lymphoma: Three illustrative cases exemplifying unique disease presentations |
| title_sort | in situ follicular neoplasia lymphoma three illustrative cases exemplifying unique disease presentations |
| topic | Follicular lymphoma follicular lymphoma in situ non-Hodgkin′s lymphoma |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=2;spage=218;epage=221;aulast=Sakhadeo |
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