Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats

Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats

Spasticity impacts the quality of life of patients suffering spinal cord injury and impedes the recovery of locomotion. At the cellular level, spasticity is considered to be primarily caused by the hyperexcitability of spinal α-motoneurons (MNs) within the spinal stretch reflex circuit. Here, we hyp...

Full description

Bibliographic Details
Main Authors: Benjun Ji, Bartosz Wojtaś, Małgorzata Skup
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
hyperexcitability
spasticity
spinal cord injury
AMPAR
NMDAR
GlyR
Online Access:https://www.mdpi.com/1422-0067/23/19/11133

Similar Items

Similar Items