Re-evaluating the Localization of Sperm-Retained Histones Revealed the Modification-Dependent Accumulation in Specific Genome Regions
Summary: The question of whether retained histones in the sperm genome localize to gene-coding regions or gene deserts has been debated for years. Previous contradictory observations are likely caused by the non-uniform sensitivity of sperm chromatin to micrococcal nuclease (MNase) digestion. Sperm...
Main Authors: | Kosuke Yamaguchi, Masashi Hada, Yuko Fukuda, Erina Inoue, Yoshinori Makino, Yuki Katou, Katsuhiko Shirahige, Yuki Okada |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-06-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718308751 |
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