In mammalian, several evidences suggest that central serotonin participates in thermoregulation. Nucleus raphe obscurus (NRO), a serotonergic nucleus, has been recognized to be the source of generation of various hemodynamic patterns in different behavioral conditions, but its involvement in thermor...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
2013-04-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000400249&lng=en&tlng=en |
| _version_ | 1818532551259586560 |
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| author | Melissa Araújo Ulhoa Nyam Florencio da Silva José Guilherme Pinheiro Pires Henrique de Azevedo Futuro Neto |
| author_facet | Melissa Araújo Ulhoa Nyam Florencio da Silva José Guilherme Pinheiro Pires Henrique de Azevedo Futuro Neto |
| author_sort | Melissa Araújo Ulhoa |
| collection | DOAJ |
| description | In mammalian, several evidences suggest that central serotonin participates in thermoregulation. Nucleus raphe obscurus (NRO), a serotonergic nucleus, has been recognized to be the source of generation of various hemodynamic patterns in different behavioral conditions, but its involvement in thermoregulation is unclear. In the present study, extracellular action potentials of NRO neurons were recorded in anesthetized rats, which were submitted to cold and warm stimuli in the tail. The firing rate of the neurons was compared before and after each stimulation. It was found that 59% of the neurons submitted to a cold stimulus trial had a significant increase in their firing frequency, while 48% of the neurons submitted to warm stimulation trial were inhibited. The opposite responses in neuronal activity of NRO units to cooling or heating suggest that these cells are involved in producing the homoeothermic vascular adaptations secondary to changes in cutaneous temperature in the rat tail. |
| first_indexed | 2024-12-11T17:47:00Z |
| format | Article |
| id | doaj.art-19f01e67606b4791b8dfb8b9f4d888e3 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-11T17:47:00Z |
| publishDate | 2013-04-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-19f01e67606b4791b8dfb8b9f4d888e32022-12-22T00:56:20ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272013-04-0171424925310.1590/0004-282X20130010S0004-282X2013000400249Melissa Araújo UlhoaNyam Florencio da SilvaJosé Guilherme Pinheiro PiresHenrique de Azevedo Futuro NetoIn mammalian, several evidences suggest that central serotonin participates in thermoregulation. Nucleus raphe obscurus (NRO), a serotonergic nucleus, has been recognized to be the source of generation of various hemodynamic patterns in different behavioral conditions, but its involvement in thermoregulation is unclear. In the present study, extracellular action potentials of NRO neurons were recorded in anesthetized rats, which were submitted to cold and warm stimuli in the tail. The firing rate of the neurons was compared before and after each stimulation. It was found that 59% of the neurons submitted to a cold stimulus trial had a significant increase in their firing frequency, while 48% of the neurons submitted to warm stimulation trial were inhibited. The opposite responses in neuronal activity of NRO units to cooling or heating suggest that these cells are involved in producing the homoeothermic vascular adaptations secondary to changes in cutaneous temperature in the rat tail.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000400249&lng=en&tlng=ennúcleo obscuro da rafeserotoninaneurônios serotoninérgicos |
| spellingShingle | Melissa Araújo Ulhoa Nyam Florencio da Silva José Guilherme Pinheiro Pires Henrique de Azevedo Futuro Neto Arquivos de Neuro-Psiquiatria núcleo obscuro da rafe serotonina neurônios serotoninérgicos |
| topic | núcleo obscuro da rafe serotonina neurônios serotoninérgicos |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000400249&lng=en&tlng=en |