Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction

<p>Abstract</p> <p>The dried flowers and buds of <it>Sophora japonica </it>are used as a medicinal herb in China, Japan and Korea to treat bleeding hemorrhoids and hematemesis. This article presents an overview of the effects of <it>Sophora japonica </it>on...

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Main Authors: Hsieh Ching-Liang, Chen Hsiang-Ni
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Chinese Medicine
Online Access:http://www.cmjournal.org/content/5/1/34
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author Hsieh Ching-Liang
Chen Hsiang-Ni
author_facet Hsieh Ching-Liang
Chen Hsiang-Ni
author_sort Hsieh Ching-Liang
collection DOAJ
description <p>Abstract</p> <p>The dried flowers and buds of <it>Sophora japonica </it>are used as a medicinal herb in China, Japan and Korea to treat bleeding hemorrhoids and hematemesis. This article presents an overview of the effects of <it>Sophora japonica </it>on cerebral infarction based on literature searched from Medline, PubMed, Cochrane Library and the China National Knowledge Infrastructure (CNKI). <it>Sophora japonica </it>contains both anti-hemorrhagic and anti-hemostatic substances. <it>Sophora japonica </it>reduces cerebral infarction partly as a result of its anti-oxidative and anti-inflammatory activities. Previous studies found that <it>Sophora japonica </it>reduced the size of cerebral infarction and neurological deficits and reduced microglial activation, interleukin-1β release and number of apoptotic cells in ischemia-reperfusion injured Sprague-Dawley rats. Further study is required to determine the relationship between <it>Sophora japonica</it>-mediated reduction in cerebral infarction size and the effects of <it>Sophora japonica </it>on platelet aggregation and cardiovascular function.</p>
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spelling doaj.art-19f0a03c1ccd41a1b1de04c48dc70c0d2022-12-22T00:27:40ZengBMCChinese Medicine1749-85462010-09-01513410.1186/1749-8546-5-34Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarctionHsieh Ching-LiangChen Hsiang-Ni<p>Abstract</p> <p>The dried flowers and buds of <it>Sophora japonica </it>are used as a medicinal herb in China, Japan and Korea to treat bleeding hemorrhoids and hematemesis. This article presents an overview of the effects of <it>Sophora japonica </it>on cerebral infarction based on literature searched from Medline, PubMed, Cochrane Library and the China National Knowledge Infrastructure (CNKI). <it>Sophora japonica </it>contains both anti-hemorrhagic and anti-hemostatic substances. <it>Sophora japonica </it>reduces cerebral infarction partly as a result of its anti-oxidative and anti-inflammatory activities. Previous studies found that <it>Sophora japonica </it>reduced the size of cerebral infarction and neurological deficits and reduced microglial activation, interleukin-1β release and number of apoptotic cells in ischemia-reperfusion injured Sprague-Dawley rats. Further study is required to determine the relationship between <it>Sophora japonica</it>-mediated reduction in cerebral infarction size and the effects of <it>Sophora japonica </it>on platelet aggregation and cardiovascular function.</p>http://www.cmjournal.org/content/5/1/34
spellingShingle Hsieh Ching-Liang
Chen Hsiang-Ni
Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction
Chinese Medicine
title Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction
title_full Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction
title_fullStr Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction
title_full_unstemmed Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction
title_short Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction
title_sort effects of it sophora japonica it flowers it huaihua it on cerebral infarction
url http://www.cmjournal.org/content/5/1/34
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