Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of Age
Objective: In this study, we aimed to evaluate the clinical, pathologic and management differences between breast cancer patients under 35 years of age and postmenopausal patients above 55 years of age.Materials and Methods: Patients who were operated on for breast cancer between November 2003 and M...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2015-07-01
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| Series: | European Journal of Breast Health |
| Subjects: | |
| Online Access: |
http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/comparison-of-clinical-and-pathological-difference/42217
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| _version_ | 1797924020939653120 |
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| author | Mustafa Emiroğlu Cem Karaali İsmail Sert Semra Salimoğlu Levent Uğurlu Süleyman Aksoy Cengiz Aydın |
| author_facet | Mustafa Emiroğlu Cem Karaali İsmail Sert Semra Salimoğlu Levent Uğurlu Süleyman Aksoy Cengiz Aydın |
| author_sort | Mustafa Emiroğlu |
| collection | DOAJ |
| description | Objective: In this study, we aimed to evaluate the clinical, pathologic and management differences between breast cancer patients under 35 years of age and postmenopausal patients above 55 years of age.Materials and Methods: Patients who were operated on for breast cancer between November 2003 and March 2013 in our hospital were retrospectively analyzed. Patients were separated into two Groups according their age; Group 1 (<35 years) and Group 2 (>55 years).Results: 94 patients with breast cancer, 45 patients in Group 1 and 49 patients in Group 2, were included in the study. The mean follow-up was 51 (19-121) months and 50 (19-120) months in Groups 1 and 2, respectively. Stages of breast cancer at the time of diagnosis were similar between the two groups. The groups were similar in terms of rates of re-excision (p=0.42), local recurrence (p=0.34) and solid organ metastases (p=0.182). The number of oncoplastic and reconstructive procedures were higher in Group 1 (p=0.04). Regarding pathological results, the rate of grade 3 tumors, those with Ki-67>12 and triple negative breast cancer were found to be higher in Group 1. In addition, the number of patients receiving chemotherapy was significantly higher in Group 1 (p=0.03).Conclusion: Oncologic results were similar between young patients and postmenopausal patients. Nevertheless, tumor biology was found to be worse in young patients. In addition, oncoplastic and reconstructive approaches were significantly higher in young patients. |
| first_indexed | 2024-04-10T14:55:09Z |
| format | Article |
| id | doaj.art-19f20fcbc33740ae98edf79735fee3b0 |
| institution | Directory Open Access Journal |
| issn | 2587-0831 |
| language | English |
| last_indexed | 2024-04-10T14:55:09Z |
| publishDate | 2015-07-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | European Journal of Breast Health |
| spelling | doaj.art-19f20fcbc33740ae98edf79735fee3b02023-02-15T16:07:23ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312015-07-0111312312710.5152/tjbh.2015.253913049054Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of AgeMustafa Emiroğlu0Cem Karaali1İsmail Sert2Semra Salimoğlu3Levent Uğurlu4Süleyman Aksoy5Cengiz Aydın6 Tepecik Eğitim ve Araştırma Hastanesi, Genel Cerrahi Anabilim Dalı, İzmir, Türkiye Tepecik Eğitim ve Araştırma Hastanesi, Genel Cerrahi Anabilim Dalı, İzmir, Türkiye Tepecik Eğitim ve Araştırma Hastanesi, Genel Cerrahi Anabilim Dalı, İzmir, Türkiye Tepecik Eğitim ve Araştırma Hastanesi, Genel Cerrahi Anabilim Dalı, İzmir, Türkiye Tepecik Eğitim ve Araştırma Hastanesi, Genel Cerrahi Anabilim Dalı, İzmir, Türkiye Tepecik Eğitim ve Araştırma Hastanesi, Genel Cerrahi Anabilim Dalı, İzmir, Türkiye Tepecik Eğitim ve Araştırma Hastanesi, Genel Cerrahi Anabilim Dalı, İzmir, Türkiye Objective: In this study, we aimed to evaluate the clinical, pathologic and management differences between breast cancer patients under 35 years of age and postmenopausal patients above 55 years of age.Materials and Methods: Patients who were operated on for breast cancer between November 2003 and March 2013 in our hospital were retrospectively analyzed. Patients were separated into two Groups according their age; Group 1 (<35 years) and Group 2 (>55 years).Results: 94 patients with breast cancer, 45 patients in Group 1 and 49 patients in Group 2, were included in the study. The mean follow-up was 51 (19-121) months and 50 (19-120) months in Groups 1 and 2, respectively. Stages of breast cancer at the time of diagnosis were similar between the two groups. The groups were similar in terms of rates of re-excision (p=0.42), local recurrence (p=0.34) and solid organ metastases (p=0.182). The number of oncoplastic and reconstructive procedures were higher in Group 1 (p=0.04). Regarding pathological results, the rate of grade 3 tumors, those with Ki-67>12 and triple negative breast cancer were found to be higher in Group 1. In addition, the number of patients receiving chemotherapy was significantly higher in Group 1 (p=0.03).Conclusion: Oncologic results were similar between young patients and postmenopausal patients. Nevertheless, tumor biology was found to be worse in young patients. In addition, oncoplastic and reconstructive approaches were significantly higher in young patients. http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/comparison-of-clinical-and-pathological-difference/42217 breast canceryoung adultpostmenopause |
| spellingShingle | Mustafa Emiroğlu Cem Karaali İsmail Sert Semra Salimoğlu Levent Uğurlu Süleyman Aksoy Cengiz Aydın Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of Age European Journal of Breast Health breast cancer young adult postmenopause |
| title | Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of Age |
| title_full | Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of Age |
| title_fullStr | Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of Age |
| title_full_unstemmed | Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of Age |
| title_short | Comparison of Clinical and Pathological Differences of Breast Cancer Patients under 35 and above 55 Years of Age |
| title_sort | comparison of clinical and pathological differences of breast cancer patients under 35 and above 55 years of age |
| topic | breast cancer young adult postmenopause |
| url |
http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/comparison-of-clinical-and-pathological-difference/42217
|
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