Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their...

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Bibliographic Details
Main Authors: Marie Ghraichy, Valentin von Niederhäusern, Aleksandr Kovaltsuk, Jacob D Galson, Charlotte M Deane, Johannes Trück
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-10-01
Series:eLife
Subjects:
B cells
repertoire
immunoglobulin
machine learning
prediction
diagnostics
Online Access:https://elifesciences.org/articles/73111

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