Reversing the immunosuppressive microenvironment with reduced redox level by microwave-chemo-immunostimulant Ce–Mn MOF for improved immunotherapy

Reversing the immunosuppressive microenvironment with reduced redox level by microwave-chemo-immunostimulant Ce–Mn MOF for improved immunotherapy

Abstract Backgrounds Reversing the immunosuppressive tumor microenvironment (TME) in the tumor is widely deemed to be an effective strategy to improve immune therapy. In particular, the redox balance in TME needs to be well controlled due to its critical role in mediating the functions of various ce...

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Bibliographic Details
Main Authors: Zhiheng Zeng, Changhui Fu, Xiaohan Sun, Meng Niu, Xiangling Ren, Longfei Tan, Qiong Wu, Zhongbing Huang, Xianwei Meng
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Nanobiotechnology
Subjects:
Ce–Mn MOF
Tumor microenvironment
Tumor-associated macrophages
Microwave therapy
Immunogenic cell death
Redox homeostasis
Online Access:https://doi.org/10.1186/s12951-022-01699-w

Internet

https://doi.org/10.1186/s12951-022-01699-w

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